Publications for Ximing Yuan
Co-author map based on ISI articles 2007-

Keywords

p53 oxidative oxidation macrophages macrophage lysosomal lung lesions ldl iron ferritin death cellular cells atherosclerotic atherosclerosis atheroma apoptotic apoptosis accumulation

Journal Articles

Maria E. Johansson, Xiao-Ying Zhang, Kristina Edfeldt, Anna M. Lundberg, Malin C. Levin, Jan Boren, Wei Li, Ximing Yuan, Lasse Folkersen, Per Eriksson, Ulf Hedin, Hann Low, Dmitri Sviridov, Francisco J. Rios, Goran K. Hansson and Zhong-Qun Yan
  Innate immune receptor NOD2 promotes vascular inflammation and formation of lipid-rich necrotic cores in hypercholesterolemic mice
  European Journal of Immunology, 2014, 44(10), 3081-3092.

Amit Laskar, Jonas Eilertsen, Wei Li and Ximing Yuan
  SPION primes THP1 derived M2 macrophages towards M1-like macrophages
  Biochemical and Biophysical Research Communications - BBRC, 2013, 441(4), 737-742.

Sayem Miah, Shahram Nour Mohammad Zadeh, Xi-Ming Yuan and Wei Li
  Expression of Egr1 and p53 in human carotid plaques and apoptosis induced by 7-oxysterol or p53.
  Experimental and Toxicological Pathology, 2013, 65(5), 677-682.
 Web of Science® Times Cited: 1

Yang Han, Yong Zhang, Lian-he Yang, Xiao-yi Mi, Shun-dong Dai, Qing-chang Li, Hong-tao Xu, Juan-han Yu, Guang Li, Jing Zhao, Chong Han, Xi-ming Yuan and En-hua Wang
  X-radiation inhibits histone deacetylase 1 and 2, upregulates Axin expression and induces apoptosis in non-small cell lung cancer
  Radiation Oncology, 2012, 7(183), .
   Fulltext  PDF  
 Web of Science® Times Cited: 3

Wei Li, Amit Laskar, Nargis Sultana, Ehab Osman, Moumita Ghosh, Qianqian Li and Ximing Yuan
  Cell death induced by 7-oxysterols via lysosomal and mitochondrial pathways is p53-dependent
  Free Radical Biology & Medicine, 2012, 53(11), 2054-2061.
 Web of Science® Times Cited: 1

Amit Laskar, Moumita Ghosh, Sikander Iqbal Khattak, Wei Li and Xi-Ming Yuan
  Degradation of superparamagnetic iron oxide nanoparticle-induced ferritin by lysosomal cathepsins and related immune response
  Nanomedicine, 2012, 7(5), 705-717.
 Web of Science® Times Cited: 6

Wei Li, Moumita Ghosh, Sina Eftekhari and Ximing Yuan
  Lipid accumulation and lysosomal pathways contribute to dysfunction and apoptosis of human endothelial cells caused by 7-oxysterols
  Biochemical and Biophysical Research Communications - BBRC, 2011, 409(4), 711-716.
 Web of Science® Times Cited: 9

Moumita Ghosh, Fredrik Carlsson, Amit Laskar, XiMing Yuan and Wei Li
  Lysosomal membrane permeabilization causes oxidative stress and ferritin induction in macrophages
  FEBS Letters, 2011, 585(4), 623-9.
 Web of Science® Times Cited: 5

Amit Laskar, XiMing Yuan and Wei Li
  Dimethyl Sulfoxide Prevents 7 beta-Hydroxycholesterol-Induced Apoptosis by Preserving Lysosomes and Mitochondria
  JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2010, 56(3), 263-267.
 Web of Science® Times Cited: 4

Xi-Ming Yuan, Ehab Osman, Sayem Miah, Shahram Nour Mohammad Zadeh, Lihua Xu, Claes Forssell and Wei Li
  p53 expression in human carotid atheroma is significantly related to plaque instability and clinical manifestations
  Atherosclerosis, 2010, 210(2), 392-399.
 Web of Science® Times Cited: 8

Xi-Ming Yuan, Ehab Osman, Sayem Miah, Shahram Nour Mohammad Zadeh, Lihua Xu, Claes Forsell and Li Wei
  p53 expression in human carotid atheroma is significantly related to plaque instability and clinical manifestations
  Atherosclerosis, 2010, 210(2), 392-399.
 Web of Science® Times Cited: 8

Y. Han, Y. Wang, H.-T. Xu, L.-H. Yang, Q. Wei, Y. Liu, Y. Zhang, Y. Zhao, S.-D. Dai, Y. Miao, J.-H. Yu, J.-Y. Zhang, G. Li, Ximing Yuan and E.-H. Wang
  X-Radiation Induces Non-Small-Cell Lung Cancer Apoptosis by Upregulation of Axin Expression
  International Journal of Radiation Oncology Biology Physics, 2009, 75(2), 518-526.
 Web of Science® Times Cited: 12

Wei Li, Henrik Johnson, Xi-Ming Yuan and Lena Jonasson
  7ß-hydroxycholesterol induces natural killer cell death via oxidative lysosomal destabilization
  Free radical research, 2009, 43(11), 1072-1079.
 Web of Science® Times Cited: 3

Wei Li, Louise Kornmark, Lena Jonasson, Claes Forssell and Ximing Yuan
  Cathepsin L is significantly associated with apoptosis and plaque destabilization in human atherosclerosis
  Atherosclerosis, 2009, 202(1), 92-102.
 Web of Science® Times Cited: 30

Karin Persson, Lilian Sauma, Annette Safholm, Lihua Xu, Wei Li and Ximing Yuan
  LDL and UV-oxidized LDL induce upregulation of iNOS and NO in unstimulated J774 macrophages and HUVEC
  Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS), 2009, 117(1), 1-9.
 Web of Science® Times Cited: 6

Wei Li, Lihua Xu, C. Forssell, J.L. Sullivan and Ximing Yuan
  Overexpression of transferrin receptor and ferritin related to clinical symptoms and destabilization of human carotid plaques
  Experimental biology and medicine (Maywood, N.J.: Print), 2008, 233(7), 818-826.
 Web of Science® Times Cited: 12

Ximing Yuan and Wei Li
  Iron involvement in multiple signaling pathways of atherosclerosis: A revisited hypothesis
  Current Medicinal Chemistry, 2008, 15(21), 2157-2172.
 Web of Science® Times Cited: 22

Wei Li, Caroline Lidebjer, Ximing Yuan, Aleksander Szymanowski, Karin Backteman, Jan Ernerudh, Per Leanderson, Lennart Nilsson, Eva Swahn and Lena Jonasson
  NK cell apoptosis in coronary artery disease. Relation to oxidative stress
  Atherosclerosis, 2008, 199(1), 65-72.
 Web of Science® Times Cited: 11

Yang Liu, Hong-Tao Xu, Shun-Dong Dai, Qiang Wei, Xi Ming Yuan and En-Hua Wang
  Reduction of p120ctn isoforms 1 and 3 is significantly associated with metastatic progression of human lung cancer
  Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS), 2007, 115(7), 848-856.
 Web of Science® Times Cited: 19

Wei Li, Mattias Östblom, Lihua Xu, A. Hellsten, Per Leanderson, Bo Liedberg, Ulf Brunk, J.W. Eaton and Ximing Yuan
  Cytocidal effects of atheromatous plaque components: The death zone revisited
  The FASEB Journal, 2006, 20(13), 2281-2290.
 Web of Science® Times Cited: 25

HT Xu, L Wang, D Lin, Yawei Liu, N Liu, Ximing Yuan and EH Wang
  Abnormal beta-catenin and reduced axin expression are associated with poor differentiation and progression in non-small cell lung cancer
  American Journal of Clinical Pathology, 2006, 125(4), 534-541.
 Web of Science® Times Cited: 32

David A Larsson, Sarah Baird, Jerome Diinga Nyhalah, Xi Ming Yuan and Wei Li
  Oxysterol mixtures, in atheroma-relevant proportions, display synergistic and proapoptotic effects
  Free Radical Biology & Medicine, 2006, 41(6), 902-910.
 Web of Science® Times Cited: 44

E-H Wang, Y Liu, S-D Dai, N Liu, C-Y Xie and Xi Ming Yuan
  Abnormal expression and clinicopathologic significance of p120-catenin in lung cancer
  Histology and Histopathology, 2006, 21( 7-9), 841-847.
 Web of Science® Times Cited: 22

Wei Li, Anna Hellsten, Lihua Xu, D-M Zhuang, Katarina Jansson, Ulf Brunk and Xi Ming Yuan
  Foam cell death induced by 7β-hydroxycholesterol is mediated by labile iron-driven oxidative injury: Mechanisms underlying induction of ferritin in human atheroma
  Free Radical Biology & Medicine, 2005, 39(7), 864-875.
 Web of Science® Times Cited: 21

EH Wang, D Lin, Y Wang, GP Wu and Ximing Yuan
  Immunohistochemical and ultrastructural markers suggest different origins for cuboidal and polygonal cells in pulmonary sclerosing hemangioma
  Human Pathology, 2004, 35(4), 503-508.
 Web of Science® Times Cited: 24

Wei Li and Ximing Yuan
  Increased expression and translocation of lysosomal cathepsins contribute to macrophage apoptosis in atherogenesis
  Annals of the New York Academy of Sciences, 2004, 1030, 427-433.
 Web of Science® Times Cited: 17

Wei Li, Anna Hellsten, JD Nyhalah and Ximing Yuan
  Enhanced expression of natural resistance-associated macrophage protein 1 in atherosclerotic lesions may be associated with oxidized lipid-induced apoptosis
  Annals of the New York Academy of Sciences, 2004, 1030, 202-207.
 Web of Science® Times Cited: 7

Wei Li, Lihua Xu and Ximing Yuan
  Macrophage hemoglobin scavenger receptor and ferritin accumulation in human atherosclerotic lesions
  Annals of the New York Academy of Sciences, 2004, 1030, 196-201.
 Web of Science® Times Cited: 8

Xi Ming Yuan, Wei Li, Sarah K Baird, Maria Carlsson and Öjar Melefors
  Secretion of ferritin by iron-laden macrophages and influence of lipoproteins
  Free radical research, 2004, 38(10), 1133-1142.
 Web of Science® Times Cited: 27

Wei Li, Anna Hellsten, Leif Jacobsson, Henrik Blomqvist, Anders Olsson and Xi Ming Yuan
  Alpha-tocopherol and astaxanthin decrease macrophage infiltration, apoptosis and vulnerability in atheroma of hyperlipidaemic rabbits
  Journal of Molecular and Cellular Cardiology, 2004, 37(5), 969-978.
 Web of Science® Times Cited: 31

Leif Jacobsson, Xi Ming Yuan, Bo Ziedén and Anders G Olsson
  Effects of α-tocopherol and astaxanthin on LDL oxidation and atherosclerosis in WHHL rabbits
  Atherosclerosis, 2004, 173(2), 231-237.
 Web of Science® Times Cited: 21

Wei Li, Ximing Yuan, S. Ivanova, K.J. Tracey, John Wallace Eaton and Ulf Brunk
  3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin
  Biochemical Journal, 2003, 371(2), 429-436.
 Web of Science® Times Cited: 46

Ximing Yuan and Wei Li
  The iron hypothesis of atherosclerosis and its clinical impact
  Annals of Medicine, 2003, 35(8), 578-591.
 Web of Science® Times Cited: 42

Xi-Ming Yuan, Wei Li, Helge Dalen, Joseph Lotem, Rachel Kama, Leo Sachs and Ulf T. Brunk
  Lysosomal destabilization in p53-induced apoptosis
  Proceedings of the National Academy of Sciences of the United States of America, 2002, 99(9), 6286-6291.

Z. Zhang, Ximing Yuan, L.-H. Li and F.-P. Xie
  Transdifferentiation of neoplastic cells
  Medical Hypotheses, 2001, 57(5), 655-666.
 Web of Science® Times Cited: 7

Z Zhang, Xi Ming Yuan, LH Li and FP Xie
  Transdifferentiation of neoplastic development and its pathological implication
  Histopathology, 2001, 16, 1249-1262.
 Web of Science® Times Cited: 9

E Dare, Wei Li, B Zhivotovsky, Xi Ming Yuan and S Ceccatelli
  Methylmercury and H2O2 provoke lysosomal damage in human astrocytoma D384 cells followed by apoptosis
  Free Radical Biology & Medicine, 2001, 30(12), 1347-1356.
 Web of Science® Times Cited: 49

Wei Li, Helge Dalen, John Wallace Eaton and Xi Ming Yuan
  Apoptotic Death of Inflammatory Cells in Human Atheroma
  Arteriosclerosis, Thrombosis and Vascular Biology, 2001, 21(7), 1124-1130.
 Web of Science® Times Cited: 68

Wei Li, XiMing Yuan, Gunnar Nordgren, Helge Dalen, Gene M. Dubowchik, Raymond A. Firestone and Ulf Brunk
  Induction of cell death by the lysosomotropic detergent MSDH
  FEBS Letters, 2000, 470(1), 35-39.
 Web of Science® Times Cited: 158

Xi Ming Yuan, Wei Li, Ulf Brunk, Helge Dalen, Yi Hsin Chang and Alex Sevanian
  Lysosomal destabilization during macrophage damage induced by cholesterol oxidation products
  Free Radical Biology & Medicine, 2000, 28(2), 208-218.
 Web of Science® Times Cited: 72

Xi Ming Yuan
  Apoptotic macrophage-derived foam cells in human atheromas are rich in iron and ferritin, suggesting iron-catalyzed reactions to be involved in apoptosis.
  Free radical research, 1999, 30, 221-231.

XiMing Yuan and Ulf Brunk
  Iron and LDL-oxidation in atherogenesis
  Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS), 1998, 106(9), 825-842.

Wei Li, Xi Ming Yuan, Anders Olsson and Ulf Brunk
  Uptake of Oxidized LDL by Macrophages Results in Partial Lysosomal Enzyme Inactivation and Relocation
  Arteriosclerosis, Thrombosis and Vascular Biology, 1998, 18(2), 177-84.

Wei Li, Ximing Yuan and Ulf Brunk
  OxLDL-induced macrophage cytotoxicity is mediated by lysosomal rupture and modified by intralysosomal redox-active iron
  Free radical research, 1998, 29(5), 389-98.

XiMing Yuan, Wei Li, Anders Olsson and Ulf Brunk
  The toxicity to macrophages of oxidized low-density lipoprotein is mediated through lysosomal damage
  Atherosclerosis, 1997, 133(2), 153-61.

Anders Olsson and XiMing Yuan
  Antioxidants in the prevention of atherosclerosis
  Current Opinion in Lipidology, 1996, 7(6), 374-80.

XiMing Yuan, Anders Olsson and Ulf Brunk
  Iron in human atheroma and LDL oxidation by macrophages following erythrophagocytosis
  Atherosclerosis, 1996, 124(1), 61-73.

XiMing Yuan, Ulf Brunk and Anders Olsson
  Effects of iron- and hemoglobin-loaded human monocyte-derived macrophages on oxidation and uptake of LDL
  Arteriosclerosis, Thrombosis and Vascular Biology, 1995, 15(9), 1345-51.

XiMing Yuan, F P Xie, Z B Lu, T X Wen, Y J Zhuang, A C Jones and Z Zhang
  The establishment of two cell lines from a mouse uterine cervical carcinoma (U14) and their metastatic phenotype changes
  Clinical and Experimental Metastasis, 1995, 13(6), 463-73.

Conference Articles

Wei Li, Ehab Osman, C Forssell and Ximing Yuan
  THROMBIN RECEPTOR (PAR1), TISSUE FACTOR AND IRON BINDING PROTEINS IN HUMAN CAROTID ATHEROSCLEROSIS
  ATHEROSCLEROSIS SUPPLEMENTS, 2009.


Wei Li, S Miah, Simon Jönsson, R Andersson and Ximing Yuan
  APOPTOSIS INDUCED BY 7B-HYDROXYCHOLESTEROL IS ASSOCIATED WITH REGULATION OF P53, B-CATENIN, AND EGR-1 in ATHEROSCLEROSIS SUPPLEMENTS, vol 10, issue 2, pp
  ATHEROSCLEROSIS SUPPLEMENTS, 2009.


Wei Li, Henrik Johnson, Ximing Yuan and Lena Jonasson
  7-beta-hydroxycholesterol induces natural killer cell death via oxidative lysosomal destalization.
  Athersclerosis 2009, 2009.


Wei Li, Xi Ming Yuan and Lena Jonasson
  Apoptosis induced by oxidized low-density lipoprotein and 7beta-hydorxycholesterol in T cells and NK cells
  XIV International Symposium on Atherosclerosis,2006, 2006.


Wei Li, Xi Ming Yuan and Lena Jonasson
  Natural killer cells in coronary artery disease - susceptibility to oxidized cholesterol
  VIII Svenska Kardiovaskulära Vårmötet,2006, 2006.


Ph.D. Theses

Amit Laskar
  Cell response to imaging contrast agents suggested for atherosclerotic plaque imaging
  2013.


  Fulltext PDF

Xi Ming Yuan
  LDL oxidation, iron, lysosomes, and macrophages in early atherosclerosis
  1997.


Licentiate Theses

Xi Ming Yuan
  Iron and macrophages in atherogenesis
  1995.