Publications for Outi Vaarala
Co-author map based on ISI articles 2007-

Publications mentioned in social media 12 times*

Keywords

© secretion risk patients milk intestinal insulin infants immune iga disease dietary diabetes cows controls children cells cd autoantibodies antibodies

Journal Articles

Jeanette Wahlberg, Outi Waarala and Johnny Ludvigsson
  Asthma and allergic symptoms and type 1 diabetes-related autoantibodies in 2.5-yr-old children
 
Altmetric usage: 3

  Pediatric Diabetes, 2011, 12(7), 604-610.
 Web of Science® Times Cited: 4

Anne Lahdenperä, Johnny Ludvigsson, Karin Fälth-Magnusson, Lotta Högberg and Outi Vaarala
  The effect of gluten-free diet on Th1--Th2--Th3-associated intestinal immune responses in celiac disease
  SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 2011, 46(5), 538-549.
 Web of Science® Times Cited: 6

Outi Vaarala, Mark A. Atkinson and Josef Neu
  The "perfect storm" for type 1 diabetes - the complex interplay between intestinal microbiota, gut permeability, and mucosal immunity
 
Altmetric usage: 7

  Diabetes, 2008, 57(10), 2555-2562.
 Web of Science® Times Cited: 119

Johnny Ludvigsson, Maria Faresjö, Maria Hjorth, Stina Axelsson, Mikael Chéramy, Mikael Pihl, Outi Vaarala, Gun Forsander, Sten Ivarsson, Calle Johansson, Agne Lindh, NO Nilsson, Jan Åman, Eva Örtqvist, Peter Zerhouni and Rosaura Casas
  GAD treatment and insulin secretion in recent-onset type 1 diabetes
 
Altmetric usage: 2

  New England Journal of Medicine, 2008, 359(18), 1909-1920.
 Web of Science® Times Cited: 234

Camilla Gullstrand, Jeanette Wahlberg Topp, Jorma Ilonen, Outi Vaarala and Johnny Ludvigsson
  Progression to type 1 diabetes and autoantibody positivity in relation to HLA-risk genotypes in children participating in the ABIS study
  Pediatric Diabetes, 2008, 9(3 PART 1), 182-190.
 Web of Science® Times Cited: 9

M Tiittanen, M Westerholm-Ormio, M Verkasalo, E Savilahti and Outi Vaarala
  Infiltration of forkhead box P3-expressing cells in small intestinal mucosa in coeliac disease but not in type 1 diabetes
  Clinical and Experimental Immunology, 2008, 152(3), 498-507.
 Web of Science® Times Cited: 37

Laura Piirainen, Saula Haahtela, Timo Helin, Riita Korpela, Tari Haahtela and Outi Vaarala
  Effect of Lactobacillus rhamnosus GG on rBet v1 and rMal d1 specific IgA in the saliva of patients with birch pollen allergy
  Annals of Allergy, Asthma & Immunology, 2008, 100(4), 338-342.

J Aittoniemi, H Turpeinen, M Tiitanen, M Knip, O Simell, J Ilonen and Outi Vaarala
  Relation among mannose-binding lectin 2 genotype, β-cell autoantibodies, and risk for type 1 diabetes in Finnish children
  Human Immunology, 2008, 69(2), 108-111.
 Web of Science® Times Cited: 8

E Marschan, J Honkanen, K Kukkonen, M Kuitunen, E Savilahti and Outi Vaarala
  Increased activation of GATA-3, IL-2 and IL-5 of cord blood mononuclear cells in infants with igE sensitization
  Pediatric Allergy and Immunology, 2008, 19(2), 132-139.

Anna Lundberg, Lars Andersson Wikberg, Jorma Ilonen, Outi Vaarala and Malin Böttcher (Fagerås)
  Lipopolysaccharide-Induced Immune Responses in Relation to the TLR4(Asp299Gly) Gene Polymorphism
  Clinical and vaccine immunology, 2008, 15(12), 1878-1883.
 Web of Science® Times Cited: 11

Jarno Honkanen, Susanne Skarsvik, Mikael Knip and Outi Vaarala
  Poor in vitro induction of FOXP3 and ICOS in type 1 cytokine environment activated T-cells from children with type 1 diabetes
  Diabetes/Metabolism Research Reviews, 2008, 24(8), 635-641.
 Web of Science® Times Cited: 10

T Rydgren, Outi Vaarala and S Sandler
  Simvastatin protects against multiple low-dose streptozotocin-induced type 1 diabetes in CD-1 mice and recurrence of disease in nonobese diabetic mice
  Journal of Pharmacology and Experimental Therapeutics, 2007, 323(1), 180-185.
 Web of Science® Times Cited: 19

Kristiina Luopajärvi, Susanne Skarsvik, Jorma Ilonen, Hans Åkerblom and Outi Vaarala
  Reduced CCR4, interleukin-13 and GATA-3 up-regulation in response to type 2 cytokines of cord blood T lymphocytes in infants at genetic risk of type 1 diabetes
  Immunology, 2007, 121(2), 189-196.
 Web of Science® Times Cited: 3

A Paananen, C Savolainen-Kopra, S Kaijalainen, Outi Vaarala, T Hovi and M Roivainen
  Genetic and phenotypic diversity of echovirus 30 strains and pathogenesis of type 1 diabetes
  Journal of Medical Virology, 2007, 79(7), 945-955.

Hanna Holmberg, Jeanette Wahlberg (Topp), Outi Vaarala and Johnny Ludvigsson
  Short duration of breast-feeding as a risk-factor for β-cell autoantibodies in 5-year-old children from the general population
  British Journal of Nutrition, 2007, 97(1), 111-116.
 Web of Science® Times Cited: 21

Antti-Pekka Laine, Hanna Holmberg, Anita Nilsson, Eva Örtqvist, Minna Kiviniemi, Outi Vaarala, Hans K Åkerblom, Olli Simell, Mikael Knip, Johnny Ludvigsson, Sten-A Ivarsson, Karin Larsson, Åke Lernmark and Jorma Ilonen
  Two insulin gene single nucleotide polymorphisms associated with type 1 diabetes risk in the Finnish and Swedish populations
  Disease Markers, 2007, 23(3), 139-45.

Outi Vaarala
  Is it dietary insulin?
  Annals of the New York Academy of Sciences, 2006, 1079, 350-359.
 Web of Science® Times Cited: 12

L Paajanen, J Kokkonen, TJ Karttunen, T Tuure, R Korpela and Outi Vaarala
  Intestinal cytokine mRNA expression in delayed-type cow's milk allergy
  Journal of Pediatric Gastroenterology and Nutrition - JPGN, 2006, 43(4), 470-476.
 Web of Science® Times Cited: 5

M Tittanden, Johanna Paronen, Erkki Savilahti, Suvi Virtanen, Jorma Ilonen, Mikael Knip, Hans Åkerblom and Outi Vaarala
  Dietary insulin as an immunogen and tolerogen
  Pediatric Allergy and Immunology, 2006, 17(7), 538-543.
 Web of Science® Times Cited: 8

Nora Pöntynen, Aaro Miettinen, T Petteri Arstila, O Kämple, Mohammad Alimohammadi, Outi Vaarala, Leena Peltonen and Ismo Ulmanen
  Aire deficient mice do not develop the same profile of tissue-specific autoantibodies as APECED patients
  Journal of Autoimmunity, 2006, 27(2), 96-104.

Miia Mäkelä, Outi Vaarala, Robert Hermann, Kimmo Salminen, Tero Vahlberg, Riita Veijola, Heikki Hyöty, Mikael Knip, Olli Simell and Jorma Ilonen
  Enteral virus infections in early childhood and an enhanced type 1 diabetes-associated antibody response to dietary insulin
  Journal of Autoimmunity, 2006, 27(1), 54-61.
 Web of Science® Times Cited: 22

Outi Vaarala, M Tiittanen, JT Huupponen and M Knip
  Insulin treatment in patients with type 1 diabetes induces upregulation of regulatory T-cell markers in peripheral blood mononuclear cells stimulated with insulin in vitro
  Diabetes, 2006, 55(12), 3446-3454.
 Web of Science® Times Cited: 20

Maria Karlsson Faresjö, Outi Vaarala, Sophie Thuswaldner, Jorma Ilonen, Ari Hinkkanen and Johnny Ludvigsson
  Diminished IFN-γ response to diabetes-associated autoantigens in children at diagnosis and during follow up of type 1 diabetes
  Diabetes/Metabolism Research Reviews, 2006, 22(6), 462-470.
 Web of Science® Times Cited: 9

Martin Ljungberg, Riita Korpela, Jorma Ilonen, Johnny Ludvigsson and Outi Vaarala
  Probiotics for the Prevention of Beta Cell Autoimmunity in Children at Genetic Risk of Type 1 Diabetes—the PRODIA Study
  Annals of the New York Academy of Sciences, 2006, 1079, 360-364.

Jeanette Wahlberg, Outi Vaarala and Johnny Ludvigsson
  Dietary risk factors for the emergence of type 1 diabetes-related autoantibodies in 2½-year-old Swedish children
  British Journal of Nutrition, 2006, 95(3), 603-608.
 Web of Science® Times Cited: 21

Jonas Ludvigsson, Maike Eylert, Jorma Ilonen, Johnny Ludvigsson and Outi Vaarala
  Effect of HLA DQ2, dietary exposure and coeliac disease on the development of antibody response to gliadin in children
  Scandinavian Journal of Gastroenterology, 2006, 41(8), 919-928.
 Web of Science® Times Cited: 3

Carl-Oscar Jonson, Maria Hedman, Maria Faresjö, Rosaura Casas, Jorma Ilonen, Johnny Ludvigsson and Outi Vaarala
  CTLA-4 Polymorfism, Type 1 Diabetes-risk Human Leukocyte Antigen-genotypes, insulin gene polymorphism and Regulatory T-cell Marker Expression in 5-year-old children
  Clinical & Experimental Immunology, 2006, 145(1), 48-55.
 Web of Science® Times Cited: 12

Hanna Holmberg, Outi Vaarala, Vaiva Sadauskaite-Kuehne, Jorma Ilonen, Žilvinas Padaiga and Johnny Ludvigsson
  Higher prevalence of autoantibodies to insulin and GAD65 in Swedish compared to Lithuanian children with type 1 diabetes
  Diabetes Research & Clinical Practice, 2006, 72(3), 308-314.
 Web of Science® Times Cited: 11

Susanne Skarsvik, Julia Puranen, Jarno Honkanen, Merja Roivainen, Jorma Ilonen, Hanna Holmberg, Johnny Ludvigsson and Outi Vaarala
  Decreased in vitro type 1 immune response against coxsackie virus B4 in children with type 1 diabetes
  Diabetes, 2006, 55(4), 996-1003.
 Web of Science® Times Cited: 24

Jeanette Wahlberg, Jenny Fredriksson (Walldén), Elisabet Nikolic, Outi Vaarala and Johnny Ludvigsson
  Environmental factors related to the induction of beta-cell autoantibodies in 1-yr-old healthy children
  Pediatric Diabetes, 2005, 6(4), 199-205.
 Web of Science® Times Cited: 7

Johanna Sjöwall, Anders Carlsson, Outi Vaarala, S. Bergstrom, Jan Ernerudh, Pia Forsberg and Christina Ekerfelt
  Innate immune responses in Lyme borreliosis: Enhanced tumour necrosis factor-a and interleukin-12 in asymptomatic individuals in response to live spirochetes
  Clinical and Experimental Immunology, 2005, 141(1), 89-98.
 Web of Science® Times Cited: 24

L Paajanen, T Tuure, Outi Vaarala and R Korpela
  Homogenization of milk has no effect on milk-specific antibodies in healthy adults
  Milchwissenschaft, 2005, 60(3), 239-241.
 Web of Science® Times Cited: 3

Outi Vaarala
  Is type 1 diabetes a disease of the gut immune system triggered by cow's milk insulin
  Advances in Experimental Medicine and Biology, 2005, 569, 151-156.
 Web of Science® Times Cited: 10

Laura Paajanen, Outi Vaarala, Riitta Karttunen, Tuula Tuure, Riitta Korpela and Jorma Kokkonen
  Increased IFN-γ secretion from duodenal biopsy samples in delayed-type cow's milk allergy
  Pediatric Allergy and Immunology, 2005, 16(5), 439-444.
 Web of Science® Times Cited: 11

Mikael Knip, Riitta Veijola, Suvi Virtanen, Heikki Hyöty, Outi Vaarala and Hans Åkerblom
  Environmental triggers and determinants of type 1 diabetes
  Diabetes, 2005, 54( SUPPL. 2), .
 Web of Science® Times Cited: 140

Mirva Viljanen, Emma Pohjavuori, Tari Haahtela, Riitta Korpela, Mikael Kuitunen, Annikki Sarnesto, Outi Vaarala and Erkki Savilahti
  Induction of inflammation as a possible mechanism of probiotic effect in atopic ezema-dermatitis syndrome
  Journal of Allergy and Clinical Immunology, 2005, 115(6), 1254-1259.

Laura Pajanen, Riita Korpela, Tuulua Tuuren, Jarno Honkanen, Irma Järvelä, Jorma Ilonen, Mikael Knip, Outi Vaarala and Jorma Kokkonen
  Cow milk is not responsible for most gastrointestinal immune-like syndromes - evidence from a population-based study.
  American Journal of Clinical Nutrition, 2005, 82(6), 1327-1335.

Erkki Savilahti, Mirjami Siltanen, Merja Kajosaari, Outi Vaarala and Kristiina Saarinen
  IgA antibodies, TGF-β1 and -β2, and Soluble CD14 in the colostrum and development of atopy by age 4
  Pediatric Research, 2005, 58(6), 1300-1305.
 Web of Science® Times Cited: 32

Hans Åkerblom, SM Virtanen, Jorma Ilonen, Errki Savilathi, Outi Vaarala, A Reunanen, K Teramo, A M Hämäläinen, J Paronen and Johnny Ludvigsson
  Dietary manipulation of beta cell autoimmunity in infants at increased risk of type 1 diabetes: A pilot study
  Diabetologia, 2005, 48(5), 829-837.
 Web of Science® Times Cited: 66

Susanne Skarsvik, Johnny Ludvigsson and Outi Vaarala
  Aberrant regulation of interleukin-12 receptor β2 chain on type 1 cytokine-stimulated T lymphocytes in type 1 diabetes
  Immunology, 2005, 114(2), 287-293.
 Web of Science® Times Cited: 7

Anneli Sepa, Jeanette Wahlberg, Outi Vaarala, Ann Frodi and Johnny Ludvigsson
  Psychological stress may induce diabetes-related autoimmunity in infancy
  Diabetes Care, 2005, 28(2), 290-295.
 Web of Science® Times Cited: 40

Outi Vaarala
  Intestinal immunity and type 1 diabetes
  Journal of Pediatric Gastroenterology and Nutrition - JPGN, 2004, 39, S732-S733.
 Web of Science® Times Cited: 2

Outi Vaarala
  Environmental causes: Dietary causes
  Endocrinology and metabolism clinics of North America (Print), 2004, 33(1), 17-26.
 Web of Science® Times Cited: 7

R Nissinen, M Leirisalo-Repo, L Halme, M Färkkilä and Outi Vaarala
  Immune activation in the small intestine in patients with rheumatoid arthritis
  Annals of the Rheumatic Diseases, 2004, 63(10), 1327-1330.
 Web of Science® Times Cited: 9

Susanne Skarsvik, Minna Tiittanen, Anna Lindström, Rosaura Casas, Johnny Ludvigsson and Outi Vaarala
  Poor in vitro maturation and pro-inflammatory cytokine response of dendritic cells in children at genetic risk of type 1 diabetes
  Scandinavian Journal of Immunology, 2004, 60(6), 647-652.
 Web of Science® Times Cited: 20

Riita Freese, Outi Vaarala, Anu Turpeinen and Marja Mutanen
  No difference in platelet activation or inflammation markers after diets rich or poor in vegetables, berries and apple in healthy subjects.
  European Journal of Nutrition, 2004, 43, 175-182.

Outi Vaarala
  Environmental causes; dietary causes.
  Endocrinology and metabolism clinics of North America (Print), 2004, 33, 17-26.

R Nissinen, M Leirisalo-Repo, R Peltomaa, T Palosuo and Outi Vaarala
  Cytokine and chemokine receptor profile of peripheral blood mononuclear cells during treatment with infliximab in patients with active rheumatoid arthritis
  Annals of the Rheumatic Diseases, 2004, 63(6), 681-687.
 Web of Science® Times Cited: 29

Emma Pohjavuori, Mirva Viljanen, Riita Korpela, Mikael Kuitunen, Minna Tiittanen, Outi Vaarala and Erkki Savilahti
  Lactobacillus GG effect in increasing IFN-gamma production in infants with cow's milk allergy.
  Journal of Allergy and Clinical Immunology, 2004, 114, 131-136.
 Web of Science® Times Cited: 165

Minna Tiittanen, Mikael Knip and Outi Vaarala
  Anti-insulin activity in IgG-fractions from children with newly-diagnosed type 1 diabetes and negative for insulin autoantibodies
  Autoimmunity, 2004, 37(1), 45-49.
 Web of Science® Times Cited: 3

Malin Fagerås Böttcher, Mounira Hmani-Aifa, Anna Lindström Lundberg, Maria Christina Jenmalm, Xiao-Mei Mai, Lennart Nilsson, Helena Aniansson Zdolsek, Bengt Björkstén, Peter Söderkvist and Outi Vaarala
  A TLR4 polymorphism is associated with asthma and reduced lipopolysaccharide-induced interleukin-12(p70) responses in Swedish children
  Journal of Allergy and Clinical Immunology, 2004, 114(3), 561-567.
 Web of Science® Times Cited: 93

T Harkonen, A Paananen, H Lankinen, T Hovi, Outi Vaarala and M Roivainen
  Enterovirus infection may induce humoral immune response reacting with islet cell autoantigens in humans
  Journal of Medical Virology, 2003, 69(3), 426-440.
 Web of Science® Times Cited: 23

B. Davydova, T. Harkonen, S. Kaialainen, T. Hovi, Outi Vaarala and M. Roivainen
  Coxsackievirus immunization delays onset of diabetes in non-obese diabetic mice
  Journal of Medical Virology, 2003, 69(4), 510-520.
 Web of Science® Times Cited: 6

A Karttunen, T Pöyry, Outi Vaarala, J Ilonen, T Hovi, M Roivainen and T Hyypiä
  Variation in enterovirus receptor genes.
  Journal of Medical Virology, 2003, 70, 99-108.

Outi Vaarala
  Immunological effects of probiotics with special reference to lactobacilli
  Clinical and Experimental Allergy, 2003, 33(12), 1634-1640.
 Web of Science® Times Cited: 60

M Westerholm-Ormio, Outi Vaarala, P Pihkala, J Ilonen and E Savilahti
  Immunologic activity in the small intestinal mucosa of pediatric patients with type 1 diabetes
  Diabetes, 2003, 52(9), 2287-2295.
 Web of Science® Times Cited: 76

H Kervinen, T Huittinen, Outi Vaarala, M Leinonen, P Saikku, V Manninen and M Mänttäri
  Antibodies to human heat shock protein 60, hypertension and dyslipidemia. A study of joint effects on coronary risk.
  Atherosclerosis, 2003, 169, 339-344.

R Nissinen, M Leirisalo-Repo, M Tiittanen, H Julkunen, H Hirvonen, T Palosuo and Outi Vaarala
  CCR3, CCR5, IL-4 and IFN-gamma expression on synovial and peripheral T-cells and monocytes in patients with rheumatoid arthritis.
  Journal of Rheumatology, 2003, 30, 1928-1934.

Salla Saijets, P Ylipaasto, Outi Vaarala, Tapani Hovi and Merja Roivainen
  Enterovirus infection and activation of human umbilical vein endothelial cells
  Journal of Medical Virology, 2003, 70(3), 430-439.
 Web of Science® Times Cited: 9

Jeanette Wahlberg, Jenny Fredriksson, Outi Vaarala and Johnny Ludvigsson
  Vaccinations may induce diabetes-related autoantibodies in one-year-old children
  Annals of the New York Academy of Sciences, 2003, 1005, 404-408.

Hanna Holmberg, Outi Vaarala, Karin Fälth-Magnusson and Johnny Ludvigsson
  Induction of diabetes-related autoantibodies below cutoff for "positivity" in young nondiabetic children
  Annals of the New York Academy of Sciences, 2003, 1005, 269-274.
 Web of Science® Times Cited: 2

Outi Vaarala
  The gut immune system and type 1 diabetes
  Annals of the New York Academy of Sciences, 2002, 958, 39-46.

Saara Vainio, Sanna Heino, Jan-Eric Månsson, Pam Fredman, Esa Kuismanen, Outi Vaarala and Elina Ikonen
  Dynamic association of human insulin receptor with lipid rafts in cells lacking caveolae.
  EMBO Reports, 2002, 3, 95-100.

Outi Vaarala, P Klemetti, S Juhela, O Simell, H Hyöty and J Ilonen
  The effect of coincident enterovirus infection and cow-s milk exposure on immunization to insulin in early infancy.
  Diabetologia, 2002, 45, 531-534.

M Blomqvist, S Juhela, S Erkkila, S Korhonen, T Simell, A Kupila, Outi Vaarala, O Simell, M Knip and J Ilonen
  Rotavirus infections and development of diabetes-associated autoantibodies during the first 2 years of life.
  Clinical and Experimental Immunology, 2002, 128, 511-515.

H.K. Akerblom, Outi Vaarala, H. Hyoty, J. Ilonen and M. Knip
  Environmental factors in the etiology of type 1 diabetes
  American Journal of Medical Genetics, 2002, 115(1), 18-29.
 Web of Science® Times Cited: 146

J Marttila, S Juhela, Outi Vaarala, H Hyöty, M Roivainen, A Hinkkanen, P Vilja, O Simell and J Ilonen
  Responses of coxsackievirus B4-specific T-cell lines to 2C protein- characterization of epitopes with special reference to the GAD65 homology region
  Virology, 2001, 284, 131-141.

H Kervinen, T Palosuo, V Manninen, L Tenkanen, Outi Vaarala and M Manttari
  Joint effects of C-reactive protein and other risk factors on acute coronary events.
  American Heart Journal, 2001, 25, 131-141.

M Halminen, S Juhela, Outi Vaarala and O Simell
  Induction of interferon-gamma and IL-4 production by mitogen and specific antigens in peripheral blood lymphocytes of Type 1 diabetes patients.
  Autoimmunity, 2001, 34, .

E Korpinen, PH Groop, JA Fagerudd, AM Teppo, H Akerblom and Outi Vaarala
  Increased secretion of TGF-beta1 by peripheral blood mononuclear cells from patients with Type 1 diabetes mellitus with diabetic nephropathy.
  Diabetic Medicine, 2001, 18, 121-125.

M Puurunen, T Palosuo, R Lassila, M Anttila and Outi Vaarala
  Immunologic and hematologic properties of antiabodies to prothrombin and plasminogen in a mouse model.
  Lupus, 2001, 10, 108-115.

Conference Articles

R Turunen, I Nupponen, H Repo, Outi Vaarala and S Andersson
  Delayed activation of CD8-positive T-cells in preterm infants to mothers with premature rupture of membranes (PROM)
  Pediatric Research, 2003.


Hanna Holmberg, Outi Vaarala, Karin Fälth-Magnusson and Johnny Ludvigsson
  Induction of diabetes-related autoantibodies below cut-off for positivity in young non-diabetic children.
  Diabetologia, 2003.


Outi Vaarala, O Tossavainen, J Paronen, M Ronkainen, J Ilonen, M Knip, SM Virtanen and HK Akerblom
  Reduced primary immunization to insulin in infants who received cow milk formula with low insulin content.
  Diabetologia, 2003.


R Turunen, I Nupponen, H Repo, Outi Vaarala and S Andersson
  Delayed activation of CD8+T-cells in preterm infants to mothers with prom
  Pediatric Research, 2003.


J. Wahlberg, J. Fredriksson, Outi Vaarala and Johnny Ludvigsson
  Vaccinations may induce diabetes-related autoantibodies in one-year-old children
  Annals of the New York Academy of Sciences, 2003.


 Web of Science® Times Cited: 15

Ph.D. Theses

Anne Lahdenperä
  Studies of Mucosal Immune Regulation in Celiac Disease and Type 1 Diabetes
  2014.


  Fulltext PDF

Anna Lundberg
  Immune responses to lipopolysaccharide in relation to allergic disease: a TLR4 gene polymorphism and endotoxin exposure
  2009.


  Fulltext PDF

Jenny Walldén (Fredriksson)
  Studies of immunological risk factors in type 1 diabetes
  2008.


  Fulltext PDF

* Social media data based on publications from 2011 to present and with a DOI; data delivered by Altmetric.com.