Publications for Marek Jan Los
Co-author map based on ISI articles 2007-

Publications mentioned in social media 17 times*

Keywords

x tumor treatment t receptor protein pathways necrosis drugs dnase dna death cells cd95 caspases caspase cancer apoptotic apoptosis activation

Journal Articles

Agata M. Wasik, Jerzy Grabarek, Aleksandar Pantovic, Artur Cieślar-Pobuda, Hamid R. Asgari, Caspar Bundgaard-Nielsen, Mehrdad Rafat, Ian M. Dixon, Saeid Ghavami and Marek Jan Los
  Chapter Five – Reprogramming and Carcinogenesis—Parallels and Distinctions
  International Review of Cell and Molecular Biology, 2014, 308, 167-203.
 Web of Science® Times Cited: 1

Saeid Ghavami, Shahla Shojaei, Behzad Yeganeh, Sudharsana R. Ande, Jaganmohan R. Jangamreddy, Maryam Mehrpour, Jonas Christoffersson, Wiem Chaabane, Adel Rezaei Moghadam, Hessam H. Kashani, Mohammad Hashemi, Ali A. Owji and Marek J Łos
  Autophagy and Apoptosis Dysfunction in Neurodegenerative Disorders
 
Altmetric usage: 4

  Progress in Neurobiology, 2014, 112, 24-49.
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 Web of Science® Times Cited: 11

Wiem Chaabane, Artur Cieślar-Pobuda, Mohamed El-Gazzah, Mayur V. Jain, Joanna Rzeszowska-Wolny, Mehrdad Rafat, Joerg Stetefeld, Saeid Ghavami and Marek Los
  Human-Gyrovirus-Apoptin Triggers Mitochondrial Death Pathway—Nur77 is Required for Apoptosis Triggering:
  Neoplasia, 2014, 16(9), 679-693.
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Oscar M. Rollano Penaloza, Magdalena Lewandowska, Joerg Stetefeld, Karolina Ossysek, Mariusz Madej, Joanna Bereta, Mateusz Sobczak, Shahla Shojaei, Saeid Ghavami and Marek Jan Los
  Apoptins: selective anticancer agents
 
Altmetric usage: 3

  Trends in Molecular Medicine, 2014, 20(9), 519-528.

Saeid Ghavami, Pawan Sharma, Behzad Yeganeh, Oluwaseun O. Ojo, Aruni Jha, Mark M. Mutawe, Hessam H. Kashani, Marek Jan Los, Thomas Klonisch, Helmut Unruh and Andrew J. Halayko
  Airway mesenchymal cell death by mevalonate cascade inhibition: integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins
  Biochimica et Biophysica Acta. Molecular Cell Research, 2014, 1843(7), 1259-1271.
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Jaganmohan Reddy Jangamreddy, Soumya Panigrahi, Kourosh Lotfi, Manisha Yadav, Subbareddy Maddika, Anil Kumar Tripathi, Sabyasachi Sanyal and Marek Jan Los
  Mapping of Apoptin interaction with BCR-ABL1, and development of apoptin-based targeted therapy
  OncoTarget, 2014, 5(16), 7198-7211.
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Artur Cieslar-Pobuda, Marcus Bäck, Karin Magnusson, Mayur Vilas Jain, Mehrdad Rafat, Saeid Ghavami, Peter R. Nilsson and Marek Jan Los
  Cell Type Related Differences in Staining with Pentameric Thiophene Derivatives
  Cytometry Part A, 2014, 85A(7), 628-635.

Artur Cieślar-Pobuda and Marek Jan Los
  Prospects and Limitations of“Click-Chemistry”-Based DNA LabelingTechnique Employing 5-Ethynyl-20deoxyuridine(EdU)
  Cytometry Part A, 2013, 83, 977-978.
 Web of Science® Times Cited: 1

Mayur V. Jain and Marek Jan Los
  Spatiotemporal cytometry—Simultaneous analysis of DNA replication and damage
  Cytometry Part A, 2013, 83, 975-976.
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 Web of Science® Times Cited: 1

Dipu Mohan Kumar, Mamoru Yamaguchi, Koshiro Miura, Mingqun Lin, Marek Los, Johannes F. Coy and Yasuko Rikihisa
  Ehrlichia chaffeensis Uses Its Surface Protein EtpE to Bind GPI-Anchored Protein DNase X and Trigger Entry into Mammalian Cells
  PLoS Pathogens, 2013, 9(10), e1003666.
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Jaganmohan Jangamreddy, Saeid Ghavami, Jerzy Grabarek, Gunnar Kratz, Emilia Wiechec, Bengt-Arne Fredriksson, Rama K. Rao, Artur Cieślar-Pobuda, Soumya Panigrahi and Marek Łos
  Salinomycin induces activation of autophagy, mitophagy and affects mitochondrial polarity: Differences between primary and cancer cells
 
Altmetric usage: 1

  Biochimica et Biophysica Acta. Molecular Cell Research, 2013, 1833(9), 2057-2069.
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 Web of Science® Times Cited: 11

Behzad Yeganeh, Mohammad Hashemi, Fredrick J. de Serres, Marek Jan Los and Saeid Ghavami
  Different Faces of Hepatocellular Carcinoma as a Health Threat in 21st Century
  Hepatitis Monthly, 2013, 13(2), .
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 Web of Science® Times Cited: 1

Mohammad Hashemi, Aliakbar Fazaeli, Saeid Ghavami, Ebrahim Eskandari-Nasab, Farshid Arbabi, Mohammad A. Mashhadi, Mohsen Taheri, Wiem Chaabane, Mayur Vilas Jain and Marek Jan Los
  Functional Polymorphisms of FAS and FASL Gene andRisk of Breast Cancer – Pilot Study of 134 Cases
 
Altmetric usage: 1

  PLoS ONE, 2013, 8(1), e53075.
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 Web of Science® Times Cited: 17

Wiem Chaabane, Sirma D. User, Mohamed El-Gazzah, Roman Jaksik, Elaheh Sajjadi, Joanna Rzeszowska-Wolny and Marek J. Łos
  Autophagy, Apoptosis, Mitoptosis and Necrosis: Interdependence Between Those Pathways and Effects on Cancer
  Archivum Immunologiae et Therapiae Experimentalis, 2013, 61(1), 43-58.
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 Web of Science® Times Cited: 33

Mayur Vilas Jain, Anna M. Paczulla, Thomas Klonisch, Florence N. Dimgba, Sahana Rao, Karin Roberg, Frank Schweizer, Claudia Lengerke, Padideh Davoodpour, Vivek R. Palicharla, Subbareddy Maddika and Marek Jan Los
  Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy development
 
Altmetric usage: 3

  Journal of Cellular and Molecular Medicine (Print), 2013, 17(1), 12-29.
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 Web of Science® Times Cited: 29

Sunil Rattan, Saeid Ghavami, Ryan H. Cunnington, Jared L. Davies, Krista L. Bathe, Behzad Yeganeh, Rakesh Arora, Marek Jan Los, Darren H. Freed, Andrew J. Halayko, Thomas Klonisch, Grant N. Pierce and Ian M. C. Dixon
  Transfat-mediated apoptosis is regulated by autophagy in primary cardiac myofibroblasts
  The FASEB Journal, 2012, 26, .

Saeid Ghavami, Ryan H Cunnington, Behzad Yeganeh, Jared J L Davies, Sunil G Rattan, Krista Bathe, Morvarid Kavosh, Marek J Los, Darren H Freed, Thomas Klonisch, Grant N Pierce, Andrew J Halayko and Ian M C Dixon
  Autophagy regulates trans fatty acid-mediated apoptosis in primary cardiac myofibroblasts.
 
Altmetric usage: 1

  Biochimica et Biophysica Acta, 2012, 1823(12), 2274-2286.
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 Web of Science® Times Cited: 5

Jaganmohan Reddy Jangamreddy and Marek J Los
  Mitoptosis, a novel mitochondrial death mechanism leading predominantly to activation of autophagy
  Hepatitis Monthly, 2012, 12(8), e6159.
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 Web of Science® Times Cited: 7

Soumya Panigrahi, Joerg Stetefeld, Jaganmohan R. Jangamreddy, Soma Mandal, Sanat K. Mandal and Marek Jan Los
  Modeling of Molecular Interaction between Apoptin, BCR-Abl and CrkL - An Alternative Approach to Conventional Rational Drug Design
 
Altmetric usage: 1

  PLoS ONE, 2012, 7(1), 6-20.
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 Web of Science® Times Cited: 6

S.M. Alavian, S.R. Ande, K.M. Coombs, B. Yeganeh, Padideh Davoodpour, M. Hashemi, Marek Jan Los and S. Ghavami
  Virus-triggered autophagy in viral hepatitis - possible novel strategies for drug development
 
Altmetric usage: 1

  Journal of Viral Hepatitis, 2011, 18(12), 821-830.
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 Web of Science® Times Cited: 15

Franklin C. Vincent and Marek Jan Los
  New potential instrument to fight hepatocellular cancer by restoring p53
  Hepatitis Monthly, 2011, 11(5), 331-332.
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 Web of Science® Times Cited: 4

Saeid Ghavami, Mark M Mutawe, Pawan Sharma, Behzad Yeganeh, Karol D McNeill, Thomas Klonisch, Helmut Unruh, Hessam H Kashani, Dedmer Schaafsma, Marek Jan Los and Andrew J Halayko
  Mevalonate Cascade Regulation of Airway Mesenchymal Cell Autophagy and Apoptosis: A Dual Role for p53
  PLOS ONE, 2011, 6(1), 0016523.
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 Web of Science® Times Cited: 27

Saeid Ghavami, Mehdi Eshragi, Sudharsana R Ande, Walter J Chazin, Thomas Klonisch, Andrew J. Halayko, Karol D Mcneill, Mohammad Hashemi, Claus Kerkhoff and Marek Jan Los
  S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3
  Cell Research, 2010, 20(3), 314-331.
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 Web of Science® Times Cited: 54

Saeid Ghavami, Mark M. Mutawe, Kristin Hauff, Gerald L. Stelmack, Dedmer Schaafsma, Pawan Sharma, Karol D. McNeill, Tyler S. Hynes, Sam K. Kung, Helmut Unruh, Thomas Klonisch, Grant M. Hatch, Marek Jan Los and Andrew J. Halayko
  Statin-triggered cell death in primary human lung mesenchyrnal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c
  Biochimica et Biophysica Acta, 2010, 1803(4), 452-467.
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 Web of Science® Times Cited: 29

O. Gökay, D. Kühner, Marek Jan Los, F. Götz, U. Bertsche and K. Albert
  An efficient approach for the isolation, identification and evaluation of antimicrobial plant components on an analytical scale, demonstrated by the example of Radix imperatoriae
  Analytical and Bioanalytical Chemistry, 2010, 398(5), 2039-2047.
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 Web of Science® Times Cited: 6

Esteban Alberti, Marek Jan Los, Rocio Garcia, JL Fraga, T. Serrano, E. Hernandez, Thomas Klonisch, R. Macías, L. Martinez, L. Castillo and K. de la Cuétara
  Prolonged Survival and expression of neural markers by bone marrow-derived stem cells transplanted into brain lesions
  Medical Science Monitor, 2009, 15(2), BR47-BR54.
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 Web of Science® Times Cited: 14

Tatiana Gurevich-Panigrahi, Emilia Wiechec, Soumya Panigrahi and Marek Jan Los
  Obesity: Pathophysiology and Clinical
  Current Medicinal Chemistry, 2009, 16(4), 506-521.
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 Web of Science® Times Cited: 25

Subbareddy Maddika, Soumya Panigrahi, Emilia Wiechec, Sebastian Wesselborg, Ute Fischer, Klaus Schulze-Osthoff and Marek Jan Los
  Unscheduled Akt-Triggered Activation of Cyclin-Dependent Kinase 2 as a Key Effector Mechanism of Apoptin's Anticancer Toxicity
  Molecular and Cellular Biology, 2009, 29(5), 1235-1248.
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 Web of Science® Times Cited: 36

Saeid Ghavami, Mehdi Eshraghi, Kamran Kadkhoda, Mark M. Mutawe, Subbareddy Maddika, Graham H. Bay, Sebastian Wesselborg, Andrew J. Halayko, Thomas Klonisch and Marek Jan Los
  Role of BNIP3 in TNF-induced cell death - TNF upregulates BNIP3 expression
  Biochimica et Biophysica Acta. Molecular Cell Research, 2009, 1793(3), 546-560.
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 Web of Science® Times Cited: 19

Marek Jan Los, Subbareddy Maddika, Bettina Erb and Klaus Schulze-Osthoff
  Switching Akt: from survival signaling to deadly response
  Bioessays, 2009, 31(5), 492-495.
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 Web of Science® Times Cited: 36

Marek Jan Los and Klaus Schulze-Osthoff
  Catching chromatin relaxation in act by flow cytometry
  Cell Cycle, 2009, 8(14), 2140-2141.
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Marek Jan Los, Soumya Panigrahi, Iran Rashedi, Sanat Mandal, Joerg Stetefeld, Frank Essmann and Klaus Schulze-Osthoff
  Apoptin, a tumor-selective killer
  Biochimica et Biophysica Acta. Molecular Cell Research, 2009, 1793(8), 1335-1342.
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 Web of Science® Times Cited: 41

Marek Jan Los
  New, exciting developments in experimental therapies in the early 21st century
  European Journal of Pharmacology, 2009, 625(1-3), 1-5.
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 Web of Science® Times Cited: 11

S. Ghavami, M. Hashemi, S. R. Ande, B. Yeganeh, W. Xiao, M. Eshraghi, C. J. Bus, K. Kadkhoda, Emilia Wiechec, A. J. Halayko and Marek Los
  Apoptosis and cancer: mutations within caspase genes
  Journal of Medical Genetics, 2009, 46(8), 497-510.
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 Web of Science® Times Cited: 154

Saeid Ghavami, Claus Kerkhoff, Walter J. Chazin, Kamran Kadhoka, Wenyan Xiao, Anne Zusea, Mohammad Hashemi, Mehdi Eshraghi, Klaus Schulze-Osthoff, Thomas Klonisch and Marek Jan Los
  S100A8/9 induces cell death via a novel, RAGE-independent pathway that involves selective release of Smac/DIABLO and Omi/HtrA2
  Biochimica et Biophysica Acta. Molecular Cell Research, 2008, 1783(2), 297-311.
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 Web of Science® Times Cited: 55

Subbareddy Maddika, Sudharsana Rao Ande, Emilia Wiechec, Lise Lotte Hansen, Sebastian Wesselborg and Marek Jan Los
  Akt-mediated phosphorylation of CDK2 regulates its dual role in cell cycle progression and apoptosis
  Journal of Cell Science, 2008, 121, 979-988.
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 Web of Science® Times Cited: 55

Subbareddy Maddika, Emilia Wiechec, S. R. Ande, I. K. Poon, Ute Fischer, Sebastian Wesselborg, D. A. Jans, Klaus Schulze-Osthoff and Marek Jan Los
  Interaction with PI3-kinase contributes to the cytotoxic activity of Apoptin
  Oncogene, 2008, 27, 3060-3065.
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 Web of Science® Times Cited: 25

Saeid Ghavami, Iran Rashedi, Brian M. Dattilo, Mehdi Eshraghi, Walter J. Chazin, Mohammad HashemI, Sebastian Wesselborg, Claus Kerkhoff and Marek Jan Los
  S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway
  Journal of Leukocyte Biology, 2008, 83(6), 1484-1492.
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 Web of Science® Times Cited: 112

Saeid Ghavami, Ahmad Asoodeh, Thomas Klonisch, Andrew J. Halayko, Kamran Kadkhoda, Tadeusz J. Kroczak, Spencer B. Gibson, Evan P. Booy, Hossein Naderi-Manesh and Marek Jan Los
  Brevinin-2R semi-selectively kills cancer cells by a distinct mechanism, which involves the lysosomal-mitochondrial death pathway
  Journal of Cellular and Molecular Medicine (Print), 2008, 12(3), 1005-1022.
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 Web of Science® Times Cited: 63

Sabine Hombach-Klonisch, Ted Paranjothy, Emilia Wiechec, Paola Pocar, Tarek Mustafa, Anja Seifert, Christian Zahl, Klaus Luis Gerlach, Katharina Biermann, Klaus Steger, Cuong Hoang-Vu, Klaus Schulze-Osthoff and Marek Jan Los
  Cancer stem cells as targets for cancer therapy: selected cancers as examples
  Archivum Immunologiae et Therapiae Experimentalis, 2008, 56(3), 165-180.
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 Web of Science® Times Cited: 25

Soumya Panigrahi, Thomas Klonisch and Marek Jan Los
  The art of killing: double stroke with apoptin and survivin as a novel approach in cancer therapy
  Cancer Biology & Therapy, 2008, 7(7), 1061-1062.
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 Web of Science® Times Cited: 3

Thomas Klonisch, Emilia Wiechec, Sabine Hombach-Klonisch, Sudharsana R. Ande, Sebastian Wesselborg, Klaus Schulze-Osthoff and Marek Jan Los
  Cancer stem cell markers in common cancers - therapeutic implications
 
Altmetric usage: 2

  Trends in Molecular Medicine, 2008, 14(10), 450-460.
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 Web of Science® Times Cited: 95

Aleksandra Glogowska, Janette Pyka, Astrid Kehlen, Marek Jan Los, Paul Perumal, Ekkehard Weber, Sheue-yann Cheng, Cuong Hoang-Vu and Thomas Klonisch
  The cytoplasmic domain of proEGF negatively regulates motility and elastinolytic activity in thyroid carcinoma cells
  Neoplasia, 2008, 10(10), 1120-1130.
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 Web of Science® Times Cited: 11

Sabine Hombach-Klonisch, Soumya Panigrahi, Iran Rashedi, Anja Seifert, Esteban Alberti, Paola Pocar, Maciej Kurpisz, Klaus Schulze-Osthoff, Andrzej Mackiewicz and Marek Jan Los
  Adult stem cells and their trans-differentiation potential-perspectives and therapeutic applications
  Journal of Molecular Medicine, 2008, 86(12), 1301-1314.
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 Web of Science® Times Cited: 53

Iran Rashedi, Soumya Panigrahi, Peyman Ezzati, Saeid Ghavami and Marek Jan Los
  Autoimmunity and apoptosis - Therapeutic implications
  Current Medicinal Chemistry, 2007, 14(29), 3139-3151.
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 Web of Science® Times Cited: 18

Subbareddy Maddika, Sudharsana Rao Ande, Soumya Panigrahi, Ted Paranjothy, Kazimierz Weglarczyk, Anne Zuse, Mehdi Eshraghi, Kamala D. Manda, Emilia Wiechec and Marek Jan Los
  Cell survival, cell death and cell cycle pathways are interconnected: Implications for cancer therapy
  Drug resistance updates, 2007, 10(1-2), 13-29.
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 Web of Science® Times Cited: 204

Mohammad Hashemi, Saeid Ghavami, Mehdi Eshraghi, Evan P. Booy and Marek Jan Los
  Cytotoxic effects of intra and extracellular zinc chelation on human breast cancer cells
  European Journal of Pharmacology, 2007, 557(1), 9-19.
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 Web of Science® Times Cited: 37

Helen K. Alexander, Evan P. Booy, Wenyan Xiao, Peyman Ezzati, Heinrich Baust and Marek Jan Los
  Selected technologies to control genes and their products for experimental and clinical purposes
  Archivum Immunologiae et Therapiae Experimentalis, 2007, 55(3), 139-149.
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 Web of Science® Times Cited: 16

Anne Zuse, Helge Prinz, Klaus Mueller, Jochen Prehn and Marek Jan Los
  Design of novel small molecule inhibitors of tubulin polymerization with high apoptosis-inclucing activity
  Molecular Cancer Therapeutics, 2007, 6(12), 3421S-3421S.

Ann Zuse, Helge Prinz, Klaus Müller, Peter Schmidt, Eckhard G. Günther, Frank Schweizer, Jochen H.M. Prehn and Marek Jan Los
  9-benzylidene-naphtho[2,3-b]thiophen-4-ones and benzylidene-9(10H)-anthracenones as novel tubulin interacting agents with high apoptosis-inducing activity
  European Journal of Pharmacology, 2007, 575(1-3), 34-45.
 Web of Science® Times Cited: 12

Subbareddy Maddika, G. H. Bay, T. J. Kroczak, Sudharsana R Ande, Emilia Wiechec, S. B. Gibson and Marek Jan Los
  Akt is transferred to the nucleus of cells treated with apoptin, and it participates in apoptin-induced cell death
  Cell Proliferation, 2007, 40(6), 835-848.
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 Web of Science® Times Cited: 28

James B. Johnston, Sri Navaratnam, Marshall W. Pitz, Jerry M. Maniate, Emilia Wiechec, Heinrich Baust, Joel Gingerich, Georgios P. Skliris, Leigh C. Murphy and Marek Jan Los
  Targeting the EGFR pathway for cancer therapy
  Current Medicinal Chemistry, 2006, 13(29), 3483-3492.
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 Web of Science® Times Cited: 89

Subbareddy Maddika, F. J. Mendoza, K. Hauff, C. R. Zamzow, T. Paranjothy and Marek Jan Los
  Cancer-selective therapy of the future: Apoptin and its mechanism of action
  Cancer Biology & Therapy, 2006, 5(1), 10-19.
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 Web of Science® Times Cited: 57

Evan P. Booy, Dina Johar, Srilekha Maddika, Hasan Pirzada, Mickey M. Sahib, Iris Gehrke, Shauna Loewen, Sherif F. Louis, Kamran Kadkhoda, Michael Mowat and Marek Jan Los
  Monoclonal and bispecific antibodies as novel therapeutics
  Archivum Immunologiae et Therapiae Experimentalis, 2006, 54(2), 85-101.
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 Web of Science® Times Cited: 13

M. Burek, Subbareddy Maddika, C. J. Burek, P. T. Daniel, Klaus Schulze-Osthoff and Marek Jan Los
  Apoptin-induced cell death is modulated by Bcl-2 family members and is Apaf-1dependent
  Oncogene, 2006, 25(15), 2213-2222.
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 Web of Science® Times Cited: 29

Tadeusz J. Kroczak, Jaroslaw Baran, Juliusz Pryjma, Maciej Siedlar, Iran Rashedi, Elizabeth Hernandez, Esteban Alberti, Subbareddy Maddika and Marek Jan Los
  The emerging importance of DNA mapping and other comprehensive screening techniques, as tools to identify new drug targets and as a means of (cancer) therapy personalisation
  Expert opinion on therapeutic targets, 2006, 10(2), 289-302.
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 Web of Science® Times Cited: 9

H. Baust, I. Schiessl, B. Mueller, F. Roedel, L. Distel, Marek Jan Los, S. Thomas and S. Rolf
  Implications for the role of PKD2 in the radiotherapy of tumours
  Strahlentherapie und Onkologie (Print), 2006, 182, 81-81.

Krzysztof Krzemieniecki, Elzbieta Szpyt, Iran Rashedi, Katarzyna Gawron and Marek Jan Los
  Targeting of solid tumors and blood malignancies by antibody-based therapies - EGFR-pathway as an example
  Central European Journal of Biology, 2006, 1(2), 167-182.
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 Web of Science® Times Cited: 12

Judy E. Anderson, Lise Lotte Hansen, Frank C. Mooren, Markus Post, Hubert Hug, Anne Zuse and Marek Jan Los
  Methods and biomarkers for the diagnosis and prognosis of cancer and other diseases: Towards personalized medicine
  Drug resistance updates, 2006, 9(4-5), 198-210.
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 Web of Science® Times Cited: 27

Shantanu Banerji and Marek Jan Los
  Important differences between topoisomerase-I and -II targeting agents
  Cancer Biology & Therapy, 2006, 5(8), 965-966.
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 Web of Science® Times Cited: 8

Jens Grote, Simone Koenig, Doreen Ackermann, Claudia Sopalla, Malgorzata Benedyk, Marek Jan Los and Claus Kerkhoff
  Identification of poly(ADP-ribose) polymerase-1 and Ku70/Ku80 as transcriptional regulators of S100A9 gene expression
  BMC Molecular Biology, 2006, 7, .
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 Web of Science® Times Cited: 19

Subbareddy Maddika, T. Kroczak and Marek Jan Los
  Apoptin triggered apoptotic signaling in cancer cells
  Annals of Oncology, 2005, 16, 36-36.

F. J. Mendoza, P. S. Espino, K. L. Cann, N. Bristow, K. McCrea and Marek Jan Los
  Anti-tumor chemotherapy utilizing peptide-based approaches - apoptotic pathways, kinases, and proteasome as targets
  Archivum Immunologiae et Therapiae Experimentalis, 2005, 53(1), 47-60.
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 Web of Science® Times Cited: 44

K. Hauff, C. Zamzow, W. J. Law, J. De Melo, K. Kennedy and Marek Jan Los
  Peptide-based approaches to treat asthma, arthritis, other autoimmune diseases and pathologies of the central nervous system
  Archivum Immunologiae et Therapiae Experimentalis, 2005, 53(4), 308-320.
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 Web of Science® Times Cited: 21

K. Barczyk, M. Kreuter, J. Pryjma, Evan P. Booy, Subbareddy Maddika, Saeid Ghavami, W. E. Berdel, J. Roth and Marek Jan Los
  Serum cytochrome c indicates in vivo apoptosis and can serve as a prognostic marker during cancer therapy
  International Journal of Cancer, 2005, 116(2), 167-173.
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 Web of Science® Times Cited: 51

Subbareddy Maddika, Evan P. Booy, Dina Johar, Spencer B. Gibson, Saeid Ghavami and Marek Jan Los
  Cancer-specific toxicity of apoptin is independent of death receptors but involves the loss of mitochondrial membrane potential and the release of mitochondrial cell-death mediators by a Nur77-dependent pathway
  Journal of Cell Science, 2005, 118, 4485-4493.
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 Web of Science® Times Cited: 58

M. Hashemi, F. Karami-Tehrani, Saeid Ghavami, Subbareddy Maddika and Marek Jan Los
  Adenosine and deoxyadenosine induces apoptosis in oestrogen receptor-positive and -negative human breast cancer cells via the intrinsic pathway
  Cell Proliferation, 2005, 38(5), 269-285.
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 Web of Science® Times Cited: 22

Saeid Ghavami, M. Hashemi, K. Kadkhoda, S. M. Alavian, G. H. Bay and Marek Jan Los
  Apoptosis in liver diseases - detection and therapeutic applications
  Medical Science Monitor, 2005, 11(11), RA337-RA345.
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 Web of Science® Times Cited: 51

M. Kreuter, C. Langer, C. Kerkhoff, P. Reddanna, A. L. Kania, Subbareddy Maddika, K. Chlichlia, T. N. Bui and Marek Jan Los
  Stroke, myocardial infarction, acute and chronic inflammatory diseases: caspases and other apoptotic molecules as targets for drug development
  Archivum Immunologiae et Therapiae Experimentalis, 2004, 52(3), 141-155.
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 Web of Science® Times Cited: 29

A. Philchenkov, M. Zavelevich, T. J. Kroczak and Marek Jan Los
  Caspases and cancer: Mechanisms of inactivation and new treatment modalities
  Experimental Oncology, 2004, 26(2), 82-97.
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 Web of Science® Times Cited: 78

Saeid Ghavami, C. Kerkhoff, Marek Jan Los, M. Hashemi, C. Sorg and F. Karami-Tehrani
  Mechanism of apoptosis induced by S100A8/A9 in colon cancer cell lines: the role of ROS and the effect of metal ions
  Journal of Leukocyte Biology, 2004, 76(1), 169-175.
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 Web of Science® Times Cited: 74

U. Cassens, G. Lewinski, A. K. Samraj, H. von Bernuth, H. Baust, K. Khazaie and Marek Jan Los
  Viral modulation of cell death by inhibition of caspases
  Archivum Immunologiae et Therapiae Experimentalis, 2003, 51(1), 19-27.
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 Web of Science® Times Cited: 20

Marek Jan Los, C. J. Burek, C. Stroh, K. Benedyk, H. Hug and A. Mackiewicz
  Anticancer drugs of tomorrow: apoptotic pathways as targets for drug design
  Drug Discovery Today, 2003, 8(2), 67-77.
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 Web of Science® Times Cited: 76

A. Renz and Marek Jan Los
  Comments on the estimation of cell membrane alteration after drug treatment by LDH release - Response
  Blood, 2003, 101(7), 2895-2895.
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H. Baust, A. Schoke, A. Brey, U. Gern, Marek Jan Los, R. M. Schmid, E. M. Röttinger and T. Seufferlein
  Evidence for radiosensitizing by gliotoxin in HL-60 cells: implications for a role of NF-kappa B independent mechanisms
  Oncogene, 2003, 22(54), 8786-8796.
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 Web of Science® Times Cited: 6

K. Sadowski-Debbing, J. F. Coy, W. Mier, H. Hug and Marek Jan Los
  Caspases - Their role in apoptosis and other physiological processes as revealed by knock-out studies
  Archivum Immunologiae et Therapiae Experimentalis, 2002, 50(1), 19-34.
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 Web of Science® Times Cited: 31

Marek Jan Los, M. Mozoluk, D. Ferrari, A. Stepczynska, C. Stroh, A. Renz, Z. Herceg, Z. Q. Wang and Klaus Schulze-Osthoff
  Activation and caspase-mediated inhibition of PARP: A molecular switch between fibroblast necrosis and apoptosis in death receptor signaling
  Molecular Biology of the Cell, 2002, 13(3), 978-988.
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 Web of Science® Times Cited: 178

K. Chlichlia, Marek Jan Los, Klaus Schulze-Osthoff, L. Gazzolo, V. Schirrmacher and K. Khazaie
  Redox events in HTLV-1 tax-induced apoptotic T-cell death
  Antioxidants and Redox Signaling, 2002, 4(3), 471-477.
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 Web of Science® Times Cited: 13

C. Stroh, U. Cassens, A. K. Samraj, W. Sibrowski, Klaus Schulze-Osthoff and Marek Jan Los
  The role of caspases in cryoinjury: caspase inhibition strongly improves the recovery of cryopreserved hematopoietic and other cells
  The FASEB Journal, 2002, 16(10), 1651-+.
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 Web of Science® Times Cited: 51

Marek Jan Los, C. Stroh, R. U. Janicke, I. H. Engels and K. Schulze-Osthoff
  Caspases: more than just killers?
  Trends in immunology, 2001, 22(1), 31-34.
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 Web of Science® Times Cited: 127

Andrea Renz, Christof Burek Burek, Walter Mier, Malgorzata Mozoluk, Klaus Schulze-Osthoff and Marek Jan Los
  Cytochrome c is rapidly extruded from apoptotic cells and detectable in serum of anticancer-drug treated tumor patients
  Advances in Experimental Medicine and Biology, 2001, 495, 331-334.

A. Renz, W. E. Berdel, M. Kreuter, C. Belka, Klaus Schulze-Osthoff and Marek Jan Los
  Rapid extracellular release of cytochrome c is specific for apoptosis and marks cell death in vivo
  Blood, 2001, 98(5), 1542-1548.
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 Web of Science® Times Cited: 94

C. J. Burek, J. Roth, H. G. Koch, K. Harzer, Marek Jan Los and Klaus Schulze-Osthoff
  The role of ceramide in receptor- and stress-induced apoptosis studied in acidic ceramidase-deficient Farber disease cells
  Oncogene, 2001, 20(45), 6493-6502.
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 Web of Science® Times Cited: 28

H. Bantel, C. Berg, M. W. Vieth, M. Stolte, W. Kruis, N. Luegering, W. Domschke, Marek Jan Los and Klaus Schulze-Osthoff
  Mesalazine inhibits activation of transcription factor NF-KB in inflamed mucosa of patients with ulcerative colitis.
  Gastroenterology, 2000, 118(4), A1116-A1116.

Marek Jan Los, D. Neubuser, J. F. Coy, M. Mozoluk, A. Poustka and Klaus Schulze-Osthoff
  Functional characterization of DNase X, a novel endonuclease expressed in muscle cells
  Biochemistry, 2000, 39(25), 7365-7373.
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 Web of Science® Times Cited: 30

D. Ferrari, Marek Jan Los, M. K. A. Bauer, P. Vandenabeele, Sebastian Wesselborg and K. Schulze-Osthoff
  P2Z purinoreceptor ligation induces activation of caspases with distinct roles in apoptotic and necrotic alterations of cell death
  FEBS Letters, 1999, 447(1), 71-75.
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 Web of Science® Times Cited: 195

Sebastian Wesselborg, I. H. Engels, E. Rossmann, Marek Jan Los and Klaus Schulze-Osthoff
  Anticancer drugs induce caspase-8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction
  Blood, 1999, 93(9), 3053-3063.
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 Web of Science® Times Cited: 248

Marek Jan Los, S. Wesselborg and K. Schulze-Osthoff
  The role of caspases in development, immunity, and apoptotic signal transduction: Lessons from knockout mice
  Immunity, 1999, 10(6), 629-639.
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 Web of Science® Times Cited: 292

C. Belka, P. Marini, A. Lepple-Wienhues, W. Budach, A. Jekle, Marek Jan Los, F. Lang, K. Schulze-Osthoff, E. Gulbins and M. Bamberg
  The tyrosine kinase Lck is required for CD95-independent caspase-8 activation and apoptosis in response to ionizing radiation
  Oncogene, 1999, 18(35), 4983-4992.
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 Web of Science® Times Cited: 72

H. Hug, Marek Jan Los, W. Hirt and K. M. Debatin
  Rhodamine 110-linked amino acids and peptides as substrates to measure caspase activity upon apoptosis induction in intact cells
  Biochemistry, 1999, 38(42), 13906-13911.
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 Web of Science® Times Cited: 90

S. Fulda, Marek Jan Los, C. Friesen and K. M. Debatin
  Chemosensitivity of solid tumor cells in vitro is related to activation of the CD95 system
  International Journal of Cancer, 1998, 76(1), 105-114.
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 Web of Science® Times Cited: 139

M. K. A. Bauer, M. Vogt, Marek Jan Los, J. Siegel, Sebastian Wesselborg and Klaus Schulze-Osthoff
  Role of reactive oxygen intermediates in activation-induced CD95 (APO-1/Fas) ligand expression
  Journal of Biological Chemistry, 1998, 273(14), 8048-8055.
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 Web of Science® Times Cited: 142

Klaus Schulze-Osthoff, D. Ferrari, Marek Jan Los, Sebastian Wesselborg and M. E. Peter
  Apoptosis signaling by death receptors
  European Journal of Biochemistry, 1998, 254(3), 439-459.
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 Web of Science® Times Cited: 671

D. Ferrari, A. Stepczynska, Marek Jan Los, Sebastian Wesselborg and Klaus Schulze-Osthoff
  Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis
  Journal of Experimental Medicine, 1998, 188(5), 979-984.
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 Web of Science® Times Cited: 163

Marek Jan Los, K. Khazaie, Klaus Schulze-Osthoff, P. A. Baeuerle, V. Schirrmacher and K. Chlichlia
  Human T cell leukemia virus-I (HTLV-I) Tax-mediated apoptosis in activated T cells requires an enhanced intracellular prooxidant state
  Journal of Immunology, 1998, 161(6), 3050-3055.
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 Web of Science® Times Cited: 43

K. M. Debatin, C. Beltinger, T. Bohler, J. Fellenberg, C. Friesen, S. Fulda, I. Herr, Marek Jan Los, C. Scheuerpflug, H. Sieverts and K. Stahnke
  Regulation of apoptosis through CD95 (APO-I/Fas) receptor-ligand interaction
  Biochemical Society Transactions, 1997, 25(2), 405-410.
 Web of Science® Times Cited: 23

E. Grage-Griebenow, J. Baran, H. Loppnow, Marek Jan Los, M. Ernst, H. D. Flad and J. Pryjma
  An Fcγ receptor I (CD64)-negative subpopulation of human peripheral blood monocytes is resistant to killing by antigen-activated CD4-positive cytotoxic T cells
  European Journal of Immunology, 1997, 27(9), 2358-2365.
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 Web of Science® Times Cited: 12

Z. Q. Wang, L. Stingl, C. Morrison, M. Jantsch, Marek Jan Los, Klaus Schulze-Osthoff and E. F. Wagner
  PARP is important for genomic stability but dispensable in apoptosis
  Genes & Development, 1997, 11(18), 2347-2358.
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 Web of Science® Times Cited: 395

Marek Jan Los, I. Herr, C. Friesen, S. Fulda, K. Schulze-Osthoff and K. M. Debatin
  Cross-resistance of CD95- and drug-induced apoptosis as a consequence of deficient activation of caspases (ICE/Ced-3 proteases)
  Blood, 1997, 90(8), 3118-3129.
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 Web of Science® Times Cited: 161

S. Fulda, C. Friesen, Marek Jan Los, C. Scaffidi, W. Mier, M. Benedict, G. Nunez, P. H. Krammer, M. E. Peter and K. M. Debatin
  Betulinic acid triggers CD95 (APO-1/Fas)- and p53-independent apoptosis via activation of caspases in neuroectodermal tumors
  Cancer Research, 1997, 57(21), 4956-4964.
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 Web of Science® Times Cited: 245

S. Fulda, C. Friesen, Marek Jan Los, M. Benedict, G. Nunez, M. E. Peter and K. M. Debatin
  CD95 (APO-1/Fas)- and p53-independent apoptosis by betulinic acid involves mitochondrial alterations and activation of caspases.
  Blood, 1997, 90(10), 2207-2207.
 Web of Science® Times Cited: 1

Klaus Schulze-Osthoff, M. K. A. Bauer, M. Vogt and Marek Jan Los
  Role of ICE-related and other proteases in Fas-mediated apoptosis
  Cell Death and Differentiation, 1996, 3(2), 177-184.
 Web of Science® Times Cited: 21

C. Friesen, I. Herr, Marek Jan Los and K. M. Debatin
  Drug induced cytotoxicity in leukemia cells involves the CD95 (APO-1/FAS) pathway of apoptosis
  British Journal of Haematology, 1996, 93, 367-367.

K. M. Debatin, C. Friesen, I. Herr and Marek Jan Los
  Activation of the CD95 pathway by anticancer drugs.
  Blood, 1996, 88(10), 2641-2641.

Marek Jan Los, J. Coy, H. Walczak and K. M. Debatin
  Activation of DNAse X - A new candidate enzyme mediating DNA fragmentation during apoptosis.
  Blood, 1996, 88(10), 266-266.

Marek Jan Los, W. Droge, K. Stricker, Pa Baeuerle and Klaus Schulze-Osthoff
  Hydrogen-Peroxide as a Potent Activator of T-Lymphocyte Functions
  European Journal of Immunology, 1995, 25(1), 159-165.
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 Web of Science® Times Cited: 150

Mo Westendorp, Va Shatrov, Klaus Schulze-Osthoff, R. Frank, M. Kraft, Marek Jan Los, Ph Krammer, W. Droge and V. Lehmann
  Hiv-1 Tat Potentiates Tnf-Induced Nf-Kappa-B Activation and Cytotoxicity
  EMBO Journal, 1995, 14(3), 546-554.
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 Web of Science® Times Cited: 307

Marek Jan Los, M. Vandecraen, Lc Penning, H. Schenk, M. Westendorp, Pa Baeuerle, W. Droge, Peter Krammer, W. Fiers and Klaus Schulze-Osthoff
  Requirement of an Ice/Ced-3 Protease for Fas/Apo-1-Mediated Apoptosis
  Nature, 1995, 375(6526), 81-83.
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 Web of Science® Times Cited: 626

Marek Jan Los, H. Schenk, K. Hexel, Pa Baeuerle, W. Droge and Klaus Schulze-Osthoff
  Il-2 Gene-Expression and Nf-Kappa-B Activation Through Cd28 Requires Reactive Oxygen Production by 5-Lipoxygenase
  EMBO Journal, 1995, 14(15), 3731-3740.
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 Web of Science® Times Cited: 232

Klaus Schulze-Osthoff, Marek Jan Los and Pa Baeuerle
  Redox Signaling by Transcription Factors Nf-Kappa-B and Ap-1 in Lymphocytes
  Biochemical Pharmacology, 1995, 50(6), 735-741.
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 Web of Science® Times Cited: 215

Marek Jan Los, W. Droge and Klaus Schulze-Osthoff
  Inhibition of Activation of Transcription Factor Ap-1 by Cd28 Signaling
  Biochemical Journal, 1994, 302, 119-123.
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 Web of Science® Times Cited: 6

Chapters in Books

Anna Savelyeva, Saeid Ghavami, Padideh Davoodpour, Asoodeh Ahmad and Marek Jan Los
  An Overview of Brevinin Superfamily: Structure, Function and Clinical Perspectives
  Anticancer Genes, Springer London, 2014, 197-212.


  Fulltext PDF

Agata M. Wasik, Jerzy Grabarek, Aleksandar Pantovic, Artur Cieslar-Pobuda, Hamid R. Asgari, Caspar Bundgaard-Nielsen, Mehrdad Rafat, Ian M. Dixon, Saeid Ghavami and Marek Jan Los
  Reprogramming and Carcinogenesis-Parallels and Distinctions
  International Review of Cell and Molecular Biology, Elsevier, 2014, 167-203.


  Fulltext PDF

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