Publications for Marek Jan Los
Co-author map based on ISI articles 2007-
Publications mentioned in social media 7 times*
Journal Articles
Behzad Yeganeh, Mohammad Hashemi, Fredrick J. de Serres, Marek Jan Los and Saeid Ghavami
Different Faces of Hepatocellular Carcinoma as a Health Threat in 21st Century
Hepatitis Monthly, 2013, 13(2), .
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Mayur Vilas Jain, Anna M. Paczulla, Thomas Klonisch, Florence N. Dimgba, Sahana Rao, Karin Roberg, Frank Schweizer, Claudia Lengerke, Padideh Davoodpour, Vivek R. Palicharla, Subbareddy Maddika and Marek Jan Los
Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy development
Journal of Cellular and Molecular Medicine (Print), 2013, 17(1), 12-29.
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Mohammad Hashemi, Aliakbar Fazaeli, Saeid Ghavami, Ebrahim Eskandari-Nasab, Farshid Arbabi, Mohammad A. Mashhadi, Mohsen Taheri, Wiem Chaabane, Mayur Vilas Jain and Marek Jan Los
Functional Polymorphisms of FAS and FASL Gene andRisk of Breast Cancer – Pilot Study of 134 Cases
PLoS ONE, 2013, 8(1), e53075.
Fulltext Web of Science® Times Cited: 1 |
Wiem Chaabane, Sirma D. User, Mohamed El-Gazzah, Roman Jaksik, Elaheh Sajjadi, Joanna Rzeszowska-Wolny and Marek J. Łos
Autophagy, Apoptosis, Mitoptosis and Necrosis: Interdependence Between Those Pathways and Effects on Cancer
Archivum Immunologiae et Therapiae Experimentalis, 2013, 61(1), 43-58.
Fulltext Web of Science® Times Cited: 2 |
Jaganmohan Jangamreddy, Saeid Ghavami, Jerzy Grabarek, Gunnar Kratz, Emilia Wiechec, Bengt-Arne Fredriksson, Rama K. Rao, Artur Cieślar-Pobuda, Soumya Panigrahi and Marek Łos
Salinomycin induces activation of autophagy, mitophagy and affects mitochondrial polarity: Differences between primary and cancer cells
Biochimica et Biophysica Acta. Molecular Cell Research, 2013, , .
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Sunil Rattan, Saeid Ghavami, Ryan H. Cunnington, Jared L. Davies, Krista L. Bathe, Behzad Yeganeh, Rakesh Arora, Marek Jan Los, Darren H. Freed, Andrew J. Halayko, Thomas Klonisch, Grant N. Pierce and Ian M. C. Dixon
Transfat-mediated apoptosis is regulated by autophagy in primary cardiac myofibroblasts
The FASEB Journal, 2012, 26, .
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Saeid Ghavami, Ryan H Cunnington, Behzad Yeganeh, Jared J L Davies, Sunil G Rattan, Krista Bathe, Morvarid Kavosh, Marek J Los, Darren H Freed, Thomas Klonisch, Grant N Pierce, Andrew J Halayko and Ian M C Dixon
Autophagy regulates trans fatty acid-mediated apoptosis in primary cardiac myofibroblasts.
Biochimica et Biophysica Acta, 2012, 1823(12), 2274-2286.
Fulltext Web of Science® Times Cited: 1 |
Jaganmohan Reddy Jangamreddy and Marek J Los
Mitoptosis, a novel mitochondrial death mechanism leading predominantly to activation of autophagy
Hepatitis Monthly, 2012, 12(8), e6159.
Fulltext Web of Science® Times Cited: 2 |
Soumya Panigrahi, Joerg Stetefeld, Jaganmohan R. Jangamreddy, Soma Mandal, Sanat K. Mandal and Marek Jan Los
Modeling of Molecular Interaction between Apoptin, BCR-Abl and CrkL - An Alternative Approach to Conventional Rational Drug Design
PLoS ONE, 2012, 7(1), 6-20.
Fulltext Web of Science® Times Cited: 3 |
S.M. Alavian, S.R. Ande, K.M. Coombs, B. Yeganeh, Padideh Davoodpour, M. Hashemi, Marek Jan Los and S. Ghavami
Virus-triggered autophagy in viral hepatitis - possible novel strategies for drug development
Journal of Viral Hepatitis, 2011, 18(12), 821-830.
Fulltext Web of Science® Times Cited: 9 |
Franklin C. Vincent and Marek Jan Los
New potential instrument to fight hepatocellular cancer by restoring p53
Hepatitis Monthly, 2011, 11(5), 331-332.
Fulltext Web of Science® Times Cited: 3 |
Saeid Ghavami, Mark M Mutawe, Pawan Sharma, Behzad Yeganeh, Karol D McNeill, Thomas Klonisch, Helmut Unruh, Hessam H Kashani, Dedmer Schaafsma, Marek Jan Los and Andrew J Halayko
Mevalonate Cascade Regulation of Airway Mesenchymal Cell Autophagy and Apoptosis: A Dual Role for p53
PLOS ONE, 2011, 6(1), 0016523.
Fulltext Web of Science® Times Cited: 18 |
Saeid Ghavami, Mehdi Eshragi, Sudharsana R Ande, Walter J Chazin, Thomas Klonisch, Andrew J. Halayko, Karol D Mcneill, Mohammad Hashemi, Claus Kerkhoff and Marek Jan Los
S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3
Cell Research, 2010, 20(3), 314-331.
Fulltext Web of Science® Times Cited: 35 |
Saeid Ghavami, Mark M. Mutawe, Kristin Hauff, Gerald L. Stelmack, Dedmer Schaafsma, Pawan Sharma, Karol D. McNeill, Tyler S. Hynes, Sam K. Kung, Helmut Unruh, Thomas Klonisch, Grant M. Hatch, Marek Jan Los and Andrew J. Halayko
Statin-triggered cell death in primary human lung mesenchyrnal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c
Biochimica et Biophysica Acta, 2010, 1803(4), 452-467.
Fulltext Web of Science® Times Cited: 22 |
O. Gökay, D. Kühner, Marek Jan Los, F. Götz, U. Bertsche and K. Albert
An efficient approach for the isolation, identification and evaluation of antimicrobial plant components on an analytical scale, demonstrated by the example of Radix imperatoriae
Analytical and Bioanalytical Chemistry, 2010, 398(5), 2039-2047.
Fulltext Web of Science® Times Cited: 5 |
Esteban Alberti, Marek Jan Los, Rocio Garcia, JL Fraga, T. Serrano, E. Hernandez, Thomas Klonisch, R. Macías, L. Martinez, L. Castillo and K. de la Cuétara
Prolonged Survival and expression of neural markers by bone marrow-derived stem cells transplanted into brain lesions
Medical Science Monitor, 2009, 15(2), BR47-BR54.
Fulltext Web of Science® Times Cited: 10 |
Tatiana Gurevich-Panigrahi, Emilia Wiechec, Soumya Panigrahi and Marek Jan Los
Obesity: Pathophysiology and Clinical
Current Medicinal Chemistry, 2009, 16(4), 506-521.
Fulltext Web of Science® Times Cited: 20 |
Subbareddy Maddika, Soumya Panigrahi, Emilia Wiechec, Sebastian Wesselborg, Ute Fischer, Klaus Schulze-Osthoff and Marek Jan Los
Unscheduled Akt-Triggered Activation of Cyclin-Dependent Kinase 2 as a Key Effector Mechanism of Apoptin's Anticancer Toxicity
Molecular and Cellular Biology, 2009, 29(5), 1235-1248.
Fulltext Web of Science® Times Cited: 29 |
Saeid Ghavami, Mehdi Eshraghi, Kamran Kadkhoda, Mark M. Mutawe, Subbareddy Maddika, Graham H. Bay, Sebastian Wesselborg, Andrew J. Halayko, Thomas Klonisch and Marek Jan Los
Role of BNIP3 in TNF-induced cell death - TNF upregulates BNIP3 expression
Biochimica et Biophysica Acta. Molecular Cell Research, 2009, 1793(3), 546-560.
Fulltext Web of Science® Times Cited: 16 |
Marek Jan Los, Subbareddy Maddika, Bettina Erb and Klaus Schulze-Osthoff
Switching Akt: from survival signaling to deadly response
Bioessays, 2009, 31(5), 492-495.
Fulltext Web of Science® Times Cited: 22 |
Marek Jan Los and Klaus Schulze-Osthoff
Catching chromatin relaxation in act by flow cytometry
Cell Cycle, 2009, 8(14), 2140-2141.
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Marek Jan Los, Soumya Panigrahi, Iran Rashedi, Sanat Mandal, Joerg Stetefeld, Frank Essmann and Klaus Schulze-Osthoff
Apoptin, a tumor-selective killer
Biochimica et Biophysica Acta. Molecular Cell Research, 2009, 1793(8), 1335-1342.
Fulltext Web of Science® Times Cited: 29 |
Marek Jan Los
New, exciting developments in experimental therapies in the early 21st century
European Journal of Pharmacology, 2009, 625(1-3), 1-5.
Fulltext Web of Science® Times Cited: 8 |
S. Ghavami, M. Hashemi, S. R. Ande, B. Yeganeh, W. Xiao, M. Eshraghi, C. J. Bus, K. Kadkhoda, Emilia Wiechec, A. J. Halayko and Marek Los
Apoptosis and cancer: mutations within caspase genes
Journal of Medical Genetics, 2009, 46(8), 497-510.
Fulltext Web of Science® Times Cited: 99 |
Saeid Ghavami, Claus Kerkhoff, Walter J. Chazin, Kamran Kadhoka, Wenyan Xiao, Anne Zusea, Mohammad Hashemi, Mehdi Eshraghi, Klaus Schulze-Osthoff, Thomas Klonisch and Marek Jan Los
S100A8/9 induces cell death via a novel, RAGE-independent pathway that involves selective release of Smac/DIABLO and Omi/HtrA2
Biochimica et Biophysica Acta. Molecular Cell Research, 2008, 1783(2), 297-311.
Fulltext Web of Science® Times Cited: 43 |
Subbareddy Maddika, Sudharsana Rao Ande, Emilia Wiechec, Lise Lotte Hansen, Sebastian Wesselborg and Marek Jan Los
Akt-mediated phosphorylation of CDK2 regulates its dual role in cell cycle progression and apoptosis
Journal of Cell Science, 2008, 121, 979-988.
Fulltext Web of Science® Times Cited: 42 |
Subbareddy Maddika, Emilia Wiechec, S. R. Ande, I. K. Poon, Ute Fischer, Sebastian Wesselborg, D. A. Jans, Klaus Schulze-Osthoff and Marek Jan Los
Interaction with PI3-kinase contributes to the cytotoxic activity of Apoptin
Oncogene, 2008, 27, 3060-3065.
Fulltext Web of Science® Times Cited: 19 |
Saeid Ghavami, Iran Rashedi, Brian M. Dattilo, Mehdi Eshraghi, Walter J. Chazin, Mohammad HashemI, Sebastian Wesselborg, Claus Kerkhoff and Marek Jan Los
S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway
Journal of Leukocyte Biology, 2008, 83(6), 1484-1492.
Fulltext Web of Science® Times Cited: 82 |
Saeid Ghavami, Ahmad Asoodeh, Thomas Klonisch, Andrew J. Halayko, Kamran Kadkhoda, Tadeusz J. Kroczak, Spencer B. Gibson, Evan P. Booy, Hossein Naderi-Manesh and Marek Jan Los
Brevinin-2R semi-selectively kills cancer cells by a distinct mechanism, which involves the lysosomal-mitochondrial death pathway
Journal of Cellular and Molecular Medicine (Print), 2008, 12(3), 1005-1022.
Fulltext Web of Science® Times Cited: 51 |
Sabine Hombach-Klonisch, Ted Paranjothy, Emilia Wiechec, Paola Pocar, Tarek Mustafa, Anja Seifert, Christian Zahl, Klaus Luis Gerlach, Katharina Biermann, Klaus Steger, Cuong Hoang-Vu, Klaus Schulze-Osthoff and Marek Jan Los
Cancer stem cells as targets for cancer therapy: selected cancers as examples
Archivum Immunologiae et Therapiae Experimentalis, 2008, 56(3), 165-180.
Fulltext Web of Science® Times Cited: 18 |
Soumya Panigrahi, Thomas Klonisch and Marek Jan Los
The art of killing: double stroke with apoptin and survivin as a novel approach in cancer therapy
Cancer Biology & Therapy, 2008, 7(7), 1061-1062.
Fulltext Web of Science® Times Cited: 3 |
Thomas Klonisch, Emilia Wiechec, Sabine Hombach-Klonisch, Sudharsana R. Ande, Sebastian Wesselborg, Klaus Schulze-Osthoff and Marek Jan Los
Cancer stem cell markers in common cancers - therapeutic implications
Trends in Molecular Medicine, 2008, 14(10), 450-460.
Fulltext Web of Science® Times Cited: 68 |
Aleksandra Glogowska, Janette Pyka, Astrid Kehlen, Marek Jan Los, Paul Perumal, Ekkehard Weber, Sheue-yann Cheng, Cuong Hoang-Vu and Thomas Klonisch
The cytoplasmic domain of proEGF negatively regulates motility and elastinolytic activity in thyroid carcinoma cells
Neoplasia, 2008, 10(10), 1120-1130.
Fulltext Web of Science® Times Cited: 8 |
Sabine Hombach-Klonisch, Soumya Panigrahi, Iran Rashedi, Anja Seifert, Esteban Alberti, Paola Pocar, Maciej Kurpisz, Klaus Schulze-Osthoff, Andrzej Mackiewicz and Marek Jan Los
Adult stem cells and their trans-differentiation potential-perspectives and therapeutic applications
Journal of Molecular Medicine, 2008, 86(12), 1301-1314.
Fulltext Web of Science® Times Cited: 40 |
Iran Rashedi, Soumya Panigrahi, Peyman Ezzati, Saeid Ghavami and Marek Jan Los
Autoimmunity and apoptosis - Therapeutic implications
Current Medicinal Chemistry, 2007, 14(29), 3139-3151.
Fulltext Web of Science® Times Cited: 16 |
Subbareddy Maddika, Sudharsana Rao Ande, Soumya Panigrahi, Ted Paranjothy, Kazimierz Weglarczyk, Anne Zuse, Mehdi Eshraghi, Kamala D. Manda, Emilia Wiechec and Marek Jan Los
Cell survival, cell death and cell cycle pathways are interconnected: Implications for cancer therapy
Drug resistance updates, 2007, 10(1-2), 13-29.
Fulltext Web of Science® Times Cited: 170 |
Mohammad Hashemi, Saeid Ghavami, Mehdi Eshraghi, Evan P. Booy and Marek Jan Los
Cytotoxic effects of intra and extracellular zinc chelation on human breast cancer cells
European Journal of Pharmacology, 2007, 557(1), 9-19.
Fulltext Web of Science® Times Cited: 32 |
Helen K. Alexander, Evan P. Booy, Wenyan Xiao, Peyman Ezzati, Heinrich Baust and Marek Jan Los
Selected technologies to control genes and their products for experimental and clinical purposes
Archivum Immunologiae et Therapiae Experimentalis, 2007, 55(3), 139-149.
Fulltext Web of Science® Times Cited: 15 |
Anne Zuse, Helge Prinz, Klaus Mueller, Jochen Prehn and Marek Jan Los
Design of novel small molecule inhibitors of tubulin polymerization with high apoptosis-inclucing activity
Molecular Cancer Therapeutics, 2007, 6(12), 3421S-3421S.
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Ann Zuse, Helge Prinz, Klaus Müller, Peter Schmidt, Eckhard G. Günther, Frank Schweizer, Jochen H.M. Prehn and Marek Jan Los
9-benzylidene-naphtho[2,3-b]thiophen-4-ones and benzylidene-9(10H)-anthracenones as novel tubulin interacting agents with high apoptosis-inducing activity
European Journal of Pharmacology, 2007, 575(1-3), 34-45.
Fulltext Web of Science® Times Cited: 8 |
Subbareddy Maddika, G. H. Bay, T. J. Kroczak, Sudharsana R Ande, Emilia Wiechec, S. B. Gibson and Marek Jan Los
Akt is transferred to the nucleus of cells treated with apoptin, and it participates in apoptin-induced cell death
Cell Proliferation, 2007, 40(6), 835-848.
Fulltext Web of Science® Times Cited: 22 |
James B. Johnston, Sri Navaratnam, Marshall W. Pitz, Jerry M. Maniate, Emilia Wiechec, Heinrich Baust, Joel Gingerich, Georgios P. Skliris, Leigh C. Murphy and Marek Jan Los
Targeting the EGFR pathway for cancer therapy
Current Medicinal Chemistry, 2006, 13(29), 3483-3492.
Fulltext Web of Science® Times Cited: 79 |
Subbareddy Maddika, F. J. Mendoza, K. Hauff, C. R. Zamzow, T. Paranjothy and Marek Jan Los
Cancer-selective therapy of the future: Apoptin and its mechanism of action
Cancer Biology & Therapy, 2006, 5(1), 10-19.
Fulltext Web of Science® Times Cited: 51 |
Evan P. Booy, Dina Johar, Srilekha Maddika, Hasan Pirzada, Mickey M. Sahib, Iris Gehrke, Shauna Loewen, Sherif F. Louis, Kamran Kadkhoda, Michael Mowat and Marek Jan Los
Monoclonal and bispecific antibodies as novel therapeutics
Archivum Immunologiae et Therapiae Experimentalis, 2006, 54(2), 85-101.
Fulltext Web of Science® Times Cited: 11 |
M. Burek, Subbareddy Maddika, C. J. Burek, P. T. Daniel, Klaus Schulze-Osthoff and Marek Jan Los
Apoptin-induced cell death is modulated by Bcl-2 family members and is Apaf-1dependent
Oncogene, 2006, 25(15), 2213-2222.
Fulltext Web of Science® Times Cited: 24 |
Tadeusz J. Kroczak, Jaroslaw Baran, Juliusz Pryjma, Maciej Siedlar, Iran Rashedi, Elizabeth Hernandez, Esteban Alberti, Subbareddy Maddika and Marek Jan Los
The emerging importance of DNA mapping and other comprehensive screening techniques, as tools to identify new drug targets and as a means of (cancer) therapy personalisation
Expert opinion on therapeutic targets, 2006, 10(2), 289-302.
Fulltext Web of Science® Times Cited: 9 |
H. Baust, I. Schiessl, B. Mueller, F. Roedel, L. Distel, Marek Jan Los, S. Thomas and S. Rolf
Implications for the role of PKD2 in the radiotherapy of tumours
Strahlentherapie und Onkologie (Print), 2006, 182, 81-81.
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Krzysztof Krzemieniecki, Elzbieta Szpyt, Iran Rashedi, Katarzyna Gawron and Marek Jan Los
Targeting of solid tumors and blood malignancies by antibody-based therapies - EGFR-pathway as an example
Central European Journal of Biology, 2006, 1(2), 167-182.
Fulltext Web of Science® Times Cited: 12 |
Judy E. Anderson, Lise Lotte Hansen, Frank C. Mooren, Markus Post, Hubert Hug, Anne Zuse and Marek Jan Los
Methods and biomarkers for the diagnosis and prognosis of cancer and other diseases: Towards personalized medicine
Drug resistance updates, 2006, 9(4-5), 198-210.
Fulltext Web of Science® Times Cited: 22 |
Shantanu Banerji and Marek Jan Los
Important differences between topoisomerase-I and -II targeting agents
Cancer Biology & Therapy, 2006, 5(8), 965-966.
Fulltext Web of Science® Times Cited: 7 |
Jens Grote, Simone Koenig, Doreen Ackermann, Claudia Sopalla, Malgorzata Benedyk, Marek Jan Los and Claus Kerkhoff
Identification of poly(ADP-ribose) polymerase-1 and Ku70/Ku80 as transcriptional regulators of S100A9 gene expression
BMC Molecular Biology, 2006, 7, .
Fulltext Web of Science® Times Cited: 15 |
Subbareddy Maddika, T. Kroczak and Marek Jan Los
Apoptin triggered apoptotic signaling in cancer cells
Annals of Oncology, 2005, 16, 36-36.
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F. J. Mendoza, P. S. Espino, K. L. Cann, N. Bristow, K. McCrea and Marek Jan Los
Anti-tumor chemotherapy utilizing peptide-based approaches - apoptotic pathways, kinases, and proteasome as targets
Archivum Immunologiae et Therapiae Experimentalis, 2005, 53(1), 47-60.
Fulltext Web of Science® Times Cited: 42 |
K. Hauff, C. Zamzow, W. J. Law, J. De Melo, K. Kennedy and Marek Jan Los
Peptide-based approaches to treat asthma, arthritis, other autoimmune diseases and pathologies of the central nervous system
Archivum Immunologiae et Therapiae Experimentalis, 2005, 53(4), 308-320.
Fulltext Web of Science® Times Cited: 20 |
K. Barczyk, M. Kreuter, J. Pryjma, Evan P. Booy, Subbareddy Maddika, Saeid Ghavami, W. E. Berdel, J. Roth and Marek Jan Los
Serum cytochrome c indicates in vivo apoptosis and can serve as a prognostic marker during cancer therapy
International Journal of Cancer, 2005, 116(2), 167-173.
Fulltext Web of Science® Times Cited: 42 |
Subbareddy Maddika, Evan P. Booy, Dina Johar, Spencer B. Gibson, Saeid Ghavami and Marek Jan Los
Cancer-specific toxicity of apoptin is independent of death receptors but involves the loss of mitochondrial membrane potential and the release of mitochondrial cell-death mediators by a Nur77-dependent pathway
Journal of Cell Science, 2005, 118, 4485-4493.
Fulltext Web of Science® Times Cited: 50 |
M. Hashemi, F. Karami-Tehrani, Saeid Ghavami, Subbareddy Maddika and Marek Jan Los
Adenosine and deoxyadenosine induces apoptosis in oestrogen receptor-positive and -negative human breast cancer cells via the intrinsic pathway
Cell Proliferation, 2005, 38(5), 269-285.
Fulltext Web of Science® Times Cited: 20 |
Saeid Ghavami, M. Hashemi, K. Kadkhoda, S. M. Alavian, G. H. Bay and Marek Jan Los
Apoptosis in liver diseases - detection and therapeutic applications
Medical Science Monitor, 2005, 11(11), RA337-RA345.
Fulltext Web of Science® Times Cited: 42 |
M. Kreuter, C. Langer, C. Kerkhoff, P. Reddanna, A. L. Kania, Subbareddy Maddika, K. Chlichlia, T. N. Bui and Marek Jan Los
Stroke, myocardial infarction, acute and chronic inflammatory diseases: caspases and other apoptotic molecules as targets for drug development
Archivum Immunologiae et Therapiae Experimentalis, 2004, 52(3), 141-155.
Fulltext Web of Science® Times Cited: 29 |
A. Philchenkov, M. Zavelevich, T. J. Kroczak and Marek Jan Los
Caspases and cancer: Mechanisms of inactivation and new treatment modalities
Experimental Oncology, 2004, 26(2), 82-97.
Fulltext Web of Science® Times Cited: 72 |
Saeid Ghavami, C. Kerkhoff, Marek Jan Los, M. Hashemi, C. Sorg and F. Karami-Tehrani
Mechanism of apoptosis induced by S100A8/A9 in colon cancer cell lines: the role of ROS and the effect of metal ions
Journal of Leukocyte Biology, 2004, 76(1), 169-175.
Fulltext Web of Science® Times Cited: 67 |
U. Cassens, G. Lewinski, A. K. Samraj, H. von Bernuth, H. Baust, K. Khazaie and Marek Jan Los
Viral modulation of cell death by inhibition of caspases
Archivum Immunologiae et Therapiae Experimentalis, 2003, 51(1), 19-27.
Fulltext Web of Science® Times Cited: 20 |
Marek Jan Los, C. J. Burek, C. Stroh, K. Benedyk, H. Hug and A. Mackiewicz
Anticancer drugs of tomorrow: apoptotic pathways as targets for drug design
Drug Discovery Today, 2003, 8(2), 67-77.
Fulltext Web of Science® Times Cited: 71 |
A. Renz and Marek Jan Los
Comments on the estimation of cell membrane alteration after drug treatment by LDH release - Response
Blood, 2003, 101(7), 2895-2895.
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H. Baust, A. Schoke, A. Brey, U. Gern, Marek Jan Los, R. M. Schmid, E. M. Röttinger and T. Seufferlein
Evidence for radiosensitizing by gliotoxin in HL-60 cells: implications for a role of NF-kappa B independent mechanisms
Oncogene, 2003, 22(54), 8786-8796.
Fulltext Web of Science® Times Cited: 6 |
K. Sadowski-Debbing, J. F. Coy, W. Mier, H. Hug and Marek Jan Los
Caspases - Their role in apoptosis and other physiological processes as revealed by knock-out studies
Archivum Immunologiae et Therapiae Experimentalis, 2002, 50(1), 19-34.
Fulltext Web of Science® Times Cited: 26 |
Marek Jan Los, M. Mozoluk, D. Ferrari, A. Stepczynska, C. Stroh, A. Renz, Z. Herceg, Z. Q. Wang and Klaus Schulze-Osthoff
Activation and caspase-mediated inhibition of PARP: A molecular switch between fibroblast necrosis and apoptosis in death receptor signaling
Molecular Biology of the Cell, 2002, 13(3), 978-988.
Fulltext Web of Science® Times Cited: 152 |
K. Chlichlia, Marek Jan Los, Klaus Schulze-Osthoff, L. Gazzolo, V. Schirrmacher and K. Khazaie
Redox events in HTLV-1 tax-induced apoptotic T-cell death
Antioxidants and Redox Signaling, 2002, 4(3), 471-477.
Fulltext Web of Science® Times Cited: 12 |
C. Stroh, U. Cassens, A. K. Samraj, W. Sibrowski, Klaus Schulze-Osthoff and Marek Jan Los
The role of caspases in cryoinjury: caspase inhibition strongly improves the recovery of cryopreserved hematopoietic and other cells
The FASEB Journal, 2002, 16(10), 1651-+.
Fulltext Web of Science® Times Cited: 41 |
Marek Jan Los, C. Stroh, R. U. Janicke, I. H. Engels and K. Schulze-Osthoff
Caspases: more than just killers?
Trends in immunology, 2001, 22(1), 31-34.
Fulltext Web of Science® Times Cited: 124 |
A. Renz, W. E. Berdel, M. Kreuter, C. Belka, Klaus Schulze-Osthoff and Marek Jan Los
Rapid extracellular release of cytochrome c is specific for apoptosis and marks cell death in vivo
Blood, 2001, 98(5), 1542-1548.
Fulltext Web of Science® Times Cited: 88 |
C. J. Burek, J. Roth, H. G. Koch, K. Harzer, Marek Jan Los and Klaus Schulze-Osthoff
The role of ceramide in receptor- and stress-induced apoptosis studied in acidic ceramidase-deficient Farber disease cells
Oncogene, 2001, 20(45), 6493-6502.
Fulltext Web of Science® Times Cited: 26 |
H. Bantel, C. Berg, M. W. Vieth, M. Stolte, W. Kruis, N. Luegering, W. Domschke, Marek Jan Los and Klaus Schulze-Osthoff
Mesalazine inhibits activation of transcription factor NF-KB in inflamed mucosa of patients with ulcerative colitis.
Gastroenterology, 2000, 118(4), A1116-A1116.
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Marek Jan Los, D. Neubuser, J. F. Coy, M. Mozoluk, A. Poustka and Klaus Schulze-Osthoff
Functional characterization of DNase X, a novel endonuclease expressed in muscle cells
Biochemistry, 2000, 39(25), 7365-7373.
Fulltext Web of Science® Times Cited: 28 |
D. Ferrari, Marek Jan Los, M. K. A. Bauer, P. Vandenabeele, Sebastian Wesselborg and K. Schulze-Osthoff
P2Z purinoreceptor ligation induces activation of caspases with distinct roles in apoptotic and necrotic alterations of cell death
FEBS Letters, 1999, 447(1), 71-75.
Fulltext Web of Science® Times Cited: 187 |
Sebastian Wesselborg, I. H. Engels, E. Rossmann, Marek Jan Los and Klaus Schulze-Osthoff
Anticancer drugs induce caspase-8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction
Blood, 1999, 93(9), 3053-3063.
Fulltext Web of Science® Times Cited: 243 |
Marek Jan Los, S. Wesselborg and K. Schulze-Osthoff
The role of caspases in development, immunity, and apoptotic signal transduction: Lessons from knockout mice
Immunity, 1999, 10(6), 629-639.
Fulltext Web of Science® Times Cited: 274 |
C. Belka, P. Marini, A. Lepple-Wienhues, W. Budach, A. Jekle, Marek Jan Los, F. Lang, K. Schulze-Osthoff, E. Gulbins and M. Bamberg
The tyrosine kinase Lck is required for CD95-independent caspase-8 activation and apoptosis in response to ionizing radiation
Oncogene, 1999, 18(35), 4983-4992.
Fulltext Web of Science® Times Cited: 71 |
H. Hug, Marek Jan Los, W. Hirt and K. M. Debatin
Rhodamine 110-linked amino acids and peptides as substrates to measure caspase activity upon apoptosis induction in intact cells
Biochemistry, 1999, 38(42), 13906-13911.
Fulltext Web of Science® Times Cited: 88 |
S. Fulda, Marek Jan Los, C. Friesen and K. M. Debatin
Chemosensitivity of solid tumor cells in vitro is related to activation of the CD95 system
International Journal of Cancer, 1998, 76(1), 105-114.
Fulltext Web of Science® Times Cited: 135 |
M. K. A. Bauer, M. Vogt, Marek Jan Los, J. Siegel, Sebastian Wesselborg and Klaus Schulze-Osthoff
Role of reactive oxygen intermediates in activation-induced CD95 (APO-1/Fas) ligand expression
Journal of Biological Chemistry, 1998, 273(14), 8048-8055.
Fulltext Web of Science® Times Cited: 136 |
Klaus Schulze-Osthoff, D. Ferrari, Marek Jan Los, Sebastian Wesselborg and M. E. Peter
Apoptosis signaling by death receptors
European Journal of Biochemistry, 1998, 254(3), 439-459.
Fulltext Web of Science® Times Cited: 644 |
D. Ferrari, A. Stepczynska, Marek Jan Los, Sebastian Wesselborg and Klaus Schulze-Osthoff
Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis
Journal of Experimental Medicine, 1998, 188(5), 979-984.
Fulltext Web of Science® Times Cited: 160 |
Marek Jan Los, K. Khazaie, Klaus Schulze-Osthoff, P. A. Baeuerle, V. Schirrmacher and K. Chlichlia
Human T cell leukemia virus-I (HTLV-I) Tax-mediated apoptosis in activated T cells requires an enhanced intracellular prooxidant state
Journal of Immunology, 1998, 161(6), 3050-3055.
Fulltext Web of Science® Times Cited: 41 |
K. M. Debatin, C. Beltinger, T. Bohler, J. Fellenberg, C. Friesen, S. Fulda, I. Herr, Marek Jan Los, C. Scheuerpflug, H. Sieverts and K. Stahnke
Regulation of apoptosis through CD95 (APO-I/Fas) receptor-ligand interaction
Biochemical Society Transactions, 1997, 25(2), 405-410.
Web of Science® Times Cited: 23 |
E. Grage-Griebenow, J. Baran, H. Loppnow, Marek Jan Los, M. Ernst, H. D. Flad and J. Pryjma
An Fcγ receptor I (CD64)-negative subpopulation of human peripheral blood monocytes is resistant to killing by antigen-activated CD4-positive cytotoxic T cells
European Journal of Immunology, 1997, 27(9), 2358-2365.
Fulltext Web of Science® Times Cited: 11 |
Z. Q. Wang, L. Stingl, C. Morrison, M. Jantsch, Marek Jan Los, Klaus Schulze-Osthoff and E. F. Wagner
PARP is important for genomic stability but dispensable in apoptosis
Genes & Development, 1997, 11(18), 2347-2358.
Fulltext Web of Science® Times Cited: 374 |
Marek Jan Los, I. Herr, C. Friesen, S. Fulda, K. Schulze-Osthoff and K. M. Debatin
Cross-resistance of CD95- and drug-induced apoptosis as a consequence of deficient activation of caspases (ICE/Ced-3 proteases)
Blood, 1997, 90(8), 3118-3129.
Fulltext Web of Science® Times Cited: 159 |
S. Fulda, C. Friesen, Marek Jan Los, C. Scaffidi, W. Mier, M. Benedict, G. Nunez, P. H. Krammer, M. E. Peter and K. M. Debatin
Betulinic acid triggers CD95 (APO-1/Fas)- and p53-independent apoptosis via activation of caspases in neuroectodermal tumors
Cancer Research, 1997, 57(21), 4956-4964.
Fulltext Web of Science® Times Cited: 223 |
S. Fulda, C. Friesen, Marek Jan Los, M. Benedict, G. Nunez, M. E. Peter and K. M. Debatin
CD95 (APO-1/Fas)- and p53-independent apoptosis by betulinic acid involves mitochondrial alterations and activation of caspases.
Blood, 1997, 90(10), 2207-2207.
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Klaus Schulze-Osthoff, M. K. A. Bauer, M. Vogt and Marek Jan Los
Role of ICE-related and other proteases in Fas-mediated apoptosis
Cell Death and Differentiation, 1996, 3(2), 177-184.
Web of Science® Times Cited: 21 |
C. Friesen, I. Herr, Marek Jan Los and K. M. Debatin
Drug induced cytotoxicity in leukemia cells involves the CD95 (APO-1/FAS) pathway of apoptosis
British Journal of Haematology, 1996, 93, 367-367.
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K. M. Debatin, C. Friesen, I. Herr and Marek Jan Los
Activation of the CD95 pathway by anticancer drugs.
Blood, 1996, 88(10), 2641-2641.
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Marek Jan Los, J. Coy, H. Walczak and K. M. Debatin
Activation of DNAse X - A new candidate enzyme mediating DNA fragmentation during apoptosis.
Blood, 1996, 88(10), 266-266.
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Marek Jan Los, W. Droge, K. Stricker, Pa Baeuerle and Klaus Schulze-Osthoff
Hydrogen-Peroxide as a Potent Activator of T-Lymphocyte Functions
European Journal of Immunology, 1995, 25(1), 159-165.
Fulltext Web of Science® Times Cited: 147 |
Mo Westendorp, Va Shatrov, Klaus Schulze-Osthoff, R. Frank, M. Kraft, Marek Jan Los, Ph Krammer, W. Droge and V. Lehmann
Hiv-1 Tat Potentiates Tnf-Induced Nf-Kappa-B Activation and Cytotoxicity
EMBO Journal, 1995, 14(3), 546-554.
Fulltext Web of Science® Times Cited: 301 |
Marek Jan Los, M. Vandecraen, Lc Penning, H. Schenk, M. Westendorp, Pa Baeuerle, W. Droge, Peter Krammer, W. Fiers and Klaus Schulze-Osthoff
Requirement of an Ice/Ced-3 Protease for Fas/Apo-1-Mediated Apoptosis
Nature, 1995, 375(6526), 81-83.
Fulltext Web of Science® Times Cited: 622 |
Marek Jan Los, H. Schenk, K. Hexel, Pa Baeuerle, W. Droge and Klaus Schulze-Osthoff
Il-2 Gene-Expression and Nf-Kappa-B Activation Through Cd28 Requires Reactive Oxygen Production by 5-Lipoxygenase
EMBO Journal, 1995, 14(15), 3731-3740.
Fulltext Web of Science® Times Cited: 220 |
Klaus Schulze-Osthoff, Marek Jan Los and Pa Baeuerle
Redox Signaling by Transcription Factors Nf-Kappa-B and Ap-1 in Lymphocytes
Biochemical Pharmacology, 1995, 50(6), 735-741.
Fulltext Web of Science® Times Cited: 213 |
Marek Jan Los, W. Droge and Klaus Schulze-Osthoff
Inhibition of Activation of Transcription Factor Ap-1 by Cd28 Signaling
Biochemical Journal, 1994, 302, 119-123.
Fulltext Web of Science® Times Cited: 6 |
Chapters in Books
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Ph.D., Lic. Theses
