Publications for Malin Lindqvist Appell
Co-author map based on ISI articles 2007-

Publications mentioned in social media 2 times*

Keywords

variants variant treatment tpmt thiopurines thiopurine sequence patients methyltransferase metabolism inflammatory genotype gene enzyme disease cells bowel adverse 6-mp (tpmt)

Journal Articles

Hazhar Karim, Malin Lindqvist Appell and Alan Fotoohi
  Comparison of three methods for measuring thiopurine methyltransferase activity in red blood cells and human leukemia cells
  Journal of chromatography. B, 2013, 939, 80-85.

Malin Lindqvist Appell, Agnieszka Wagner and Ulf Hindorf
  A skewed thiopurine metabolism is a common clinical phenomenon that can be successfully managed with a combination of low-dose azathioprine and allopurinol
  Journal of Crohn's & Colitis, 2013, 7(6), 510-513.

Malin Lindqvist Appell, Jonathan Berg, John Duley, William E. Evans, Martin A: Kennedy, Lynne Lennard, Tony Marinaki, Howard L. McLeod, Mary V. Relling, Elke Schaeffeler, Matthias Schwab, Richard Weinshilboum, Allen E J Yeoh, Ellen M. McDonagh, Joan M. Hebert, Teri E. Klein and Sally A. Coulthard
  Nomenclature for alleles of the thiopurine methyltransferase gene
 
Altmetric usage: 2

  Pharmacogenetics & Genomics, 2013, 23(4), 242-248.
 Web of Science® Times Cited: 5

Patricia Wennerstrand, Lars-Göran Mårtensson, Stefan Söderhäll, Malin Lindqvist Appell and Anna Zimdahl
  Methotrexate binds to recombinant thiopurine S-methyltransferase and inhibits enzyme activity after high-dose infusions in childhood leukaemia
  European Journal of Clinical Pharmacology, 2013, 69(9), 1641-1649.

Ulf Hindorf and Malin Lindqvist Appell
  Letter: TPMT status determination: The simplest is the most effective? Reply: Reply to Dr. Chouchana's letter
  Journal of Crohn's and Colitis, 2012, 6(7), 808-808.

Patricia Wennerstrand, Paolo Dametto, Janosch Hennig, Therése Klingstedt, Karin Skoglund, Malin Lindqvist Appell and Lars-Göran Mårtensson
  Structural Characteristics Determine the Cause of the Low Enzyme Activity of Two Thiopurine S-Methyltransferase Allelic Variants: A Biophysical Characterization of TPMT*2 and TPMT*5
  Biochemistry, 2012, 51(30), 5912-5920.
 Web of Science® Times Cited: 2

Ulf Hindorf and Malin Lindqvist Appell
  Genotyping should be considered the primary choice for pre-treatment evaluation of thiopurine methyltransferase function
  Journal of Crohn's and Colitis, 2012, 6(6), 655-659.
   Fulltext  PDF  
 Web of Science® Times Cited: 5

Sally A Coulthard, Christopher P F Redfern, Malin Lindqvist Appell, Karin Skoglund, Ingrid Jakobsen Falk, Andrew G Hall, Gordon A Taylor and Linda A Hogarth
  Increased Sensitivity to Thiopurines in Methylthioadenosine Phosphorylase-Deleted Cancers
  MOLECULAR CANCER THERAPEUTICS, 2011, 10(3), 495-504.
 Web of Science® Times Cited: 6

Malin Lindqvist Appell, Patricia Wennerstrand, Curt Peterson, Erik Hertervig and Lars-Göran Mårtensson
  Characterization of a novel sequence variant, TPMT*28, in the human thiopurine methyltransferase gene
  Pharmacogenetics and genomics, 2010, 20(11), 700-707.
 Web of Science® Times Cited: 10

Malin Lindqvist Appell, Karin Skoglund, Anna Karlgren, Curt Peterson, Peter Söderkvist, Irene Kidhall and Sven Almer
  Explaining TPMT genotype/phenotype discrepancy by haplotyping of TPMT*3A and identification of a novel sequence variant, TPMT*23
  Pharmacogenetics and Genomics, 2007, 17(10), 891-895.
 Web of Science® Times Cited: 25

Malin Lindqvist Appell, Ulf Hindorf, Sven Almer and Curt Peterson
  Thiopurines in inflammatory bowel disease - The role of pharmacogenetics and therapeutic drug monitoring
  Current Pharmacogenomics, 2006, 4(4), 285-300.

Ulf Hindorf, Malin Lindqvist Appell, Hans Hildebrand, Ulrika Fagerberg and Sven Almer
  Adverse events leading to modification of therapy in a large cohort of patients with inflammatory bowel disease
  Alimentary Pharmacology and Therapeutics, 2006, 24(2), 331-342.
 Web of Science® Times Cited: 53

Alan Kambiz Fotoohi, Malin Lindqvist Appell, Curt Peterson and Freidoun Albertioni
  Impaired transport as a mechanism of resistance to thiopurines in human T-lymphoblastic leukemia cells
  Nucleosides, Nucleotides & Nucleic Acids, 2006, 25(9-11), 1039-1044.
 Web of Science® Times Cited: 1

Alan Kambiz Fotoohi, Malin Lindqvist Appell, Curt Peterson and Freidoun Albertioni
  Involvement of the concentrative nucleoside transporter 3 and equilibrative nucleoside transporter 2 in the resistance of T-lymphoblastic cell lines to thiopurines
  Biochemical and Biophysical Research Communications - BBRC, 2006, 343(1), 208-215.
 Web of Science® Times Cited: 30

Malin Lindqvist Appell, U Hindorf, Sven Almer, Peter Söderkvist, Magnus Ström, Henrik Hjortswang and Curt Peterson
  No induction of thiopurine methyltransferase during thiopurine treatment in inflammatory bowel disease
  Nucleosides, Nucleotides & Nucleic Acids, 2006, 25(9-11), 1033-1037.
 Web of Science® Times Cited: 10

Ulf Hindorf, Malin Lindqvist Appell, Curt Peterson, Peter Söderkvist, Magnus Ström, Henrik Hjortswang, A Pousette and Sven Almer
  Pharmacogenetics during standardised initiation of thiopurine treatment in inflammatory bowel disease
  Gut, 2006, 55(10), 1423-1431.
 Web of Science® Times Cited: 74

Malin Lindqvist Appell
  Pharmacogenetic studies of thiopurines - focus on thiopurine methyltransferase
  Gastrokuriren, 2005, 10, .

Sofie Haglund, Malin Lindqvist Appell, Sven Almer, Curt Peterson and J. Taipalensuu
  Pyrosequencing of TPMT Alleles in a General Swedish Population and in Patients with Inflammatory Bowel Disease
  Clinical Chemistry, 2004, 50(2), 288-295.
 Web of Science® Times Cited: 45

Malin Lindqvist Appell, Sofie Haglund, Sven Almer, Curt Peterson, Jan Taipalensuu, Erik Hertervig, Ebbe Lyrenäs and Peter Söderkvist
  Identification of two novel sequence variants affecting thiopurine methyltransferase enzyme activity
  Pharmacogenetics, 2004, 14(4), 261-265.
 Web of Science® Times Cited: 51

Malin Lindqvist Appell, Sven Almer, Curt Peterson and Peter Söderkvist
  Real-time RT-PCR methodology for quantification of thiopurine methyltransferase gene expression
  European Journal of Clinical Pharmacology, 2003, 59(3), 207-211.
 Web of Science® Times Cited: 6

Conference Articles

Sally Coulthard, Christopher Redfern, Svante Vikingsson, Malin Lindqvist Appell, Karin Skoglund, Ingrid Jakobsen Falk, Andrew Hall, Gordon Taylor and Linda Hogarth
  Increased sensitivity to thiopurines in methylthioadenosine phosphorylase-deleted cancers in PURINERGIC SIGNALLING, vol 6, issue , pp 33-33
  PURINERGIC SIGNALLING, 2010.


Malin Lindqvist Appell, Patricia Wennerstrand, Karin Skoglund, Mårtensson Lars-Göran, Erik Hertervig and Curt Peterson
  Explaining TPMT genotype/phenotype discrepancy by identification of a novel sequence variant, TPMT*27
  13th International Symposium on Purine and Pyrimidine metabolism in man, 2009.


Malin Lindqvist Appell, Karin Skoglund, Erik Hertervig, Peter Söderkvist and Curt Peterson
  Explaining TPMT genotype/phenotype discrepancy by identification of a novel sequence variant, TPMT*26
  Pharmacogenomics meeting Cold Spring Harbor Laboratory, 2008.


Karin Skoglund, Malin Lindqvist Appell, Sven Almér, Curt Peterson and Peter Söderkvist
  Low Expression of TPMT wild type alleles in a patient with absent TPMT activity
  UICC World Cancer Congress, 2008.


Karin Skoglund, Malin Lindqvist Appell, Sven Almér, Curt Peterson and Peter Söderkvist
  Low expression of TPMT wild type alleles in a patient with absent TPMT activity
  Pharmacogenomics, 2008.


Karin Skoglund, Malin Lindqvist Appell, Anna Karlgren, Peter Söderkvist, Curt Peterson, Irene Kidhall and Sven Almér
  Explaining TPMT Genotype/Phenotype Discrepancy by Identification of a Novel Sequence Variant, TPMT*23
  12th International Symposium on Purine and Pyrimidine Metabolism in Man, 2007.


Martin Fransson, Peter Fritzson, Malin Lindqvist Appell, Ulf Hindorf, Sven Almer and Curt Peterson
  A preliminary study of modeling and simulation in individualized drug dosage – azathioprine on inflammatory bowel disease
  SIMS 2006: Proceedings of the 47th Conference on Simulation and Modelling, Helsinki, Finland, 2007.


  Fulltext PDF

Ulf Hindorf, Malin Lindqvist Appell, Curt Peterson, Peter Söderkvist, Magnus Ström, Henrik Hjortswang, Anneli Pousette and Sven Almer
  High methylthioinosine monophosphate levels as a cause of myelotoxicity when introducing thiopurine therapy in patients with inflammatory bowel disease
  13th United European Gastroenterology week,2005, 2005.


Malin Lindqvist Appell, Ulf Hindorf, Sven Almer, Peter Söderkvist, Magnus Ström, Henrik Hjortswang and Curt Peterson
  No induction of thiopurine methyltransferase (TPMT) during thiopurine treatment in IBD
  10th Symposium European Society for the Study of Purine and Pyrimidine Metabolism in Man,2005, 2005.


Malin Lindqvist Appell, Ulf Hindorf, Sven Almer, Peter Söderkvist, Magnus Ström, Henrik Hjortswang and Curt Peterson
  No induction of thiopurine methyltransferase (TPMT) during thiopurine treatment in IBD
  13th United European Gastroenterology week,2005, 2005.


Anna Lena Zackrisson, Malin Lindqvist Appell and Curt Peterson
  Development of a real-time PCR method for quantification of mdr-1 gene expression.
  Abstracts "Analysdagarna", The Swedish Chemical Society Analytical Division.,2001, 2001.


Malin Lindqvist Appell, Birgitta Pettersson, Sven Almer, Freidoun Albertioni, Stefan Söderhäll and Curt Peterson
  The role of TPMT polymorphism for thiopurine metabolism and clinical effects.
  European society for the study of purine and pyrimidine metabolism in Man.,2001, 2001.


Henrik Gréen, Malin Lindqvist Appell, Anna Lena Zackrisson, Gunnar Juliusson and Curt Peterson
  P-gp and mdr-1 mRNA in leukemic cells fromAML patients during chemotheraphy.
  Proceedings of the American Association for Cancer Research,2001, 2001.


Ph.D. Theses

Patricia Wennerstrand
  Biophysical Characterization of Thiopurine S-Methyltransferase: A Key enzyme in the Effects of Thiopurine Drugs
  2012.


Malin Lindqvist Appell
  Pharmacogenetic studies of thiopurines: focus on thiopurine methyltransferase
  2005.


  Fulltext PDF

* Social media data based on publications from 2011 to present and with a DOI; data delivered by Altmetric.com.