Publications for Lars-Göran Mårtensson
Co-author map based on ISI articles 2007-

Keywords

variants variant unfolding tpmt thiopurine spin protein native mutations mutants mexr labels ii) hca gene enzyme disulfide carbonic anhydrase (hca

Journal Articles

Patricia Wennerstrand, Lars-Göran Mårtensson, Stefan Söderhäll, Malin Lindqvist Appell and Anna Zimdahl
  Methotrexate binds to recombinant thiopurine S-methyltransferase and inhibits enzyme activity after high-dose infusions in childhood leukaemia
  European Journal of Clinical Pharmacology, 2013, 69(9), 1641-1649.

Malin Lindqvist Appell, Patricia Wennerstrand, Curt Peterson, Erik Hertervig and Lars-Göran Mårtensson
  Characterization of a novel sequence variant, TPMT*28, in the human thiopurine methyltransferase gene
  Pharmacogenetics and genomics, 2010, 20(11), 700-707.
 Web of Science® Times Cited: 10

Cecilia Andrésen, Shah Jalal, Daniel Aili, Yi Wang, Sohidul Islam, Anngelica Jarl, Bo Liedberg, Bengt Wretlind, Lars-Göran Mårtensson and Maria Sunnerhagen
  Critical biophysical properties in the Pseudomonas aeruginosa efflux gene regulator MexR are targeted by mutations conferring multidrug resistance
  Protein Science, 2010, 19(4), 680-692.
 Web of Science® Times Cited: 4

Patricia Wennerstrand, Lars-Göran Mårtensson, P Dametto, Janosch Hennig, Karin Skoglund and Curt Peterson
  Different mechanisms behind low enzyme activity in vivo of two different variants of Thiopurine S-methyltransferase, TPMT
  The FEBS Journal, 2010, 277(Suppl. 1), 257-258.

Karin Almstedt, Lars-Göran Mårtensson, Uno Carlsson and Per Hammarström
  Thermodynamic interrogation of a folding disease. Mutant mapping of position 107 in human carbonic anhydrase II linked to marble brain disease.
  Biochemistry, 2008, 47(5), 1288-1298.
 Web of Science® Times Cited: 3

Gunnar Höst, Lars-Göran Mårtensson and Bengt-Harald Jonsson
  Redesign of human carbonic anhydrase II for increased esterase activity and specificity towards esters with long acyl chains
  Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 2006, 1764(10), 1601-1606.
   Fulltext  PDF  
 Web of Science® Times Cited: 13

Martin Karlsson, Lars-Göran Mårtensson, Carin Karlsson and Uno Carlsson
  Denaturant-assisted formation of a stabilizing disulfide bridge from engineered cysteines in nonideal conformations
  Biochemistry, 2005, 44(9), 3487-3493.
 Web of Science® Times Cited: 8

Martin Karlsson, Lars-Göran Mårtensson, Patrik Olofsson and Uno Carlsson
  Circumnavigating misfolding traps in the energy landscape through protein engineering: suppression of molten globule and aggregation in carbonic anhydrase
  Biochemistry, 2004, 43(21), 6803-6807.
 Web of Science® Times Cited: 8

Lars-Göran Mårtensson, Martin Karlsson and Uno Carlsson
  Dramatic stabilization of the native state of human carbonic anhydrase II by an engineered disulfide bond
  Biochemistry, 2002, 41(52), 15867-15875.
 Web of Science® Times Cited: 19

Malin Persson, JR Harbridge, Per Hammarström, R Mitri, Lars-Göran Mårtensson, Uno Carlsson, GR Eaton and SS Eaton
  Comparison of electron paramagnetic resonance methods to determine distances between spin labels on human carbonic anhydrase II
  Biophysical Journal, 2001, 80(6), 2886-2897.
 Web of Science® Times Cited: 53

Per Hammarström, Rikard Owenius, Lars-Göran Mårtensson, Uno Carlsson and M Lindgren
  High-resolution probing of local conformational changes in proteins by the use of multiple labeling: Unfolding and self-assembly of human carbonic anhydrase II monitored by spin, fluorescent, and chemical reactivity probes
  Biophysical Journal, 2001, 80(6), 2867-2885.
 Web of Science® Times Cited: 25

M. Huber, M. Lindgren, Per Hammarström, Lars-Göran Mårtensson, G.R. Eaton and S.S. Eaton
  Phase memory relaxation times of spin labels in human carbonic anhydrase II: Pulsed EPR to determine spin label location
  Biophysical Chemistry, 2001, 94(3), 245-256.
 Web of Science® Times Cited: 13

Sofia Svedhem, Karin Enander, Martin Karlsson, Hans Sjöbom, Bo Liedberg, Stefan Löfås, Lars-Göran Mårtensson, Sven-Erik Sjöstrand, Stefan Svensson, Uno Carlsson and Ingemar Lundström
  Subtle differences in dissociation rates of interactions between destabilized human carbonic anhydrase II mutants and immobilized benzenesulfonamide inhibitors probed by a surface plasmon resonance biosensor
  Analytical Biochemistry, 2001, 296(2), 188-196.
 Web of Science® Times Cited: 13

Martin Karlsson, Lars-Göran Mårtensson, Bengt-Harald Jonsson and Uno Carlsson
  Adsorption of human carbonic anhydrase II variants to silica nanoparticles occur stepwise: binding is followed by successive conformational changes to a molten-globule-like state
  Langmuir, 2000, 16(22), 8470-8479.
 Web of Science® Times Cited: 36

Per Hammarström, Malin Persson, Per-Ola Freskgård, Lars-Göran Mårtensson, D. Andersson, Bengt-Harald Jonsson and Uno Carlsson
  Structural mapping of an aggregation nucleation site in a molten-globule intermediate
  Journal of Biological Chemistry, 1999, 274, 32897-32903.

Conference Articles

Malin Lindqvist Appell, Patricia Wennerstrand, Karin Skoglund, Mårtensson Lars-Göran, Erik Hertervig and Curt Peterson
  Explaining TPMT genotype/phenotype discrepancy by identification of a novel sequence variant, TPMT*27
  13th International Symposium on Purine and Pyrimidine metabolism in man, 2009.


Uno Carlsson, Thomas Magnusson, Lars-Göran Mårtensson, Maria Sunnerhagen, Magdalena Svensson and Lena Tibell
  To design a novel protein: A CDIO experience in Molecular Biotechnology at Linköping University
  2nd International CDIO Conference, Linköping, 13-14 June, 2006, 2006.


Uno Carlsson, Per Hammarström, M Lindgren, M Persson, Per-Ola Freskgård, Lars-Göran Mårtensson, D Andersson, Bengt-Harald Jonsson and Magdalena Svensson
  Aggregation is site-specific in carbonic anhydrase and is prevented by GroEL: The interaction leads to a more flexible structure of both the protein substrate and the chaperonin.
  Biophysical Journal, 2000.


M Huber, Rikard Owenius, Per Hammarström, Lars-Göran Mårtensson and Uno Carlsson
  High-field (95 GHz) EPR on spin labels in human carbonic anhydrase II: Perspectives of pulsed and CW EPR
  Biophysical Journal, 2000.


Ph.D. Theses

Patricia Wennerstrand
  Biophysical Characterization of Thiopurine S-Methyltransferase: A Key enzyme in the Effects of Thiopurine Drugs
  2012.


Gunnar Höst
  Engineering carbonic anhydrase for highly selective ester hydrolysis
  2007.


  Fulltext PDF