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Publications for Ioannis Spyrou

Co-author map based on Web of Sciences articles 2007-

Publications mentioned in social media 244 times*

Journal Articles

Björn Ingelsson, Daniel Söderberg, Tobias Strid, Anita Söderberg, Ann-Charlotte Bergh, Vesa-Matti Loitto, Kourosh Lotfi, Mårten Segelmark, Giannis Spyrou and Anders Rosén
  Lymphocytes eject interferogenic mitochondrial DNA webs in response to CpG and non-CpG oligodeoxynucleotides of class C
  Proceedings of the National Academy of Sciences of the United States of America, 2018, 115(3), E478-E487.
   Fulltext  PDF  
 Web of Science® Times Cited: 2

Ivan Nalvarte, Anastasios E. Damdimopoulos, Joelle Ruegg and Ioannis Spyrou
  The expression and activity of thioredoxin reductase 1 splice variants v1 and v2 regulate the expression of genes associated with differentiation and adhesion
  Bioscience Reports, 2015, 35(e00269), .
   Fulltext  PDF  
 Web of Science® Times Cited: 3

E. Diamanti, S. Mathieu, C. Jeanneau, E. Kitraki, P. Panopoulos, G. Spyrou and I. About
  Endoplasmic reticulum stress and mineralization inhibition mechanism by the resinous monomer HEMA
  International Endodontic Journal, 2013, 46(2), 160-168.

Eleni Chantzoura, Efthimios Prinarakis, Dimitris Panagopoulos, George Mosialos and Giannis Spyrou
  Glutaredoxin-1 regulates TRAF6 activation and the IL-1 receptor/TLR4 signalling
  Biochemical and Biophysical Research Communications - BBRC, 2010, 403(3-4), 335-339.
 Web of Science® Times Cited: 15

Christophoros G Thomas and Giannis Spyrou
  ERdj5 sensitizes neuroblastoma cells to endoplasmic reticulum stress-induced apoptosis
  Journal of Biological Chemistry, 2009, 284(10), 6282-6290.
 Web of Science® Times Cited: 18

Anna-Maria G Psarra, Stefan Hermann, George Panayotou and Giannis Spyrou
  Interaction of mitochondrial thioredoxin with glucocorticoid receptor and NF-κB modulates glucocorticoid receptor and NF-κB signalling in HEK-293 cells
  Biochemical Journal, 2009, 422(3), 521-531.
 Web of Science® Times Cited: 21

Anastasios E. Damdimopoulos, Giannis Spyrou and Jan-Åke Gustafsson
  Ligands differentially modify the nuclear mobility of estrogen receptors alpha and beta
  Endocrinology, 2008, 149(1), 339-345.
 Web of Science® Times Cited: 17

Efthimios Prinarakis, Eleni Chantzoura, Dimitris Thanos and Giannis Spyrou
  S-glutathionylation of IRF3 regulates IRF3-CBP interaction and activation of the IFN beta pathway
  EMBO Journal, 2008, 27(6), 865-875.
 Web of Science® Times Cited: 43

Jie Zhou, Chantzoura Eleni, Giannis Spyrou and Bernhard Brüne
  The mitochondrial thioredoxin system regulates nitric oxide-induced HIF-1a protein
  Free Radical Biology & Medicine, 2008, 44(1), 91-98.
 Web of Science® Times Cited: 18

P. Cunnea, AP Fernandes, A. Capitanio, S. Eken, Giannis Spyrou and M. Björnstedt
  Increased expression of specific thioredoxin family proteins; a pilot immunohistochemical study on human hepatocellular carcinoma
  International journal of immunopathology and pharmacology, 2007, 20(1), 17-24.
 Web of Science® Times Cited: 19

Anastasios E. Damdimopoulos, Jan-Åke Gustafsson and Giannis Spyrou
  Nuclear immobilization of DsRed1 tagged proteins: a novel tool for studying DNA-protein interactions?
  Biochimica et Biophysica Acta, 2007, 1773(6), 687-690.
 Web of Science® Times Cited: 1

Jolanta Sroka, Agata Antosik, Jarosław Czyz, Ivan Nalvarte, Jerker M. Olsson, Giannis Spyrou and Zbigniew Madeja
  Overexpression of thioredoxin reductase 1 inhibits migration of HEK-293 cells
  Biology of the Cell, 2007, 99(12), 677-687.
 Web of Science® Times Cited: 16

Jie Zhou, Anastassios E. Damdimopoulos, Giannis Spyrou and Bernhard Brüne
  Thioredoxin 1 and Thioredoxin 2 Have Opposed Regulatory Functions on Hypoxia-inducible Factor-1α*
  Journal of Biological Chemistry, 2007, 282(10), 7482-7490.
 Web of Science® Times Cited: 42

Anna-Maria G. Psarra, Sylvia Solakidi, Ioannis P. Trougakos, Loukas H. Margaritis, Giannis Spyrou and Constantine E. Sekeris
  Glucocorticoid receptor isoforms in human hepatocarcinoma HepG2 and SaOS-2 osteosarcoma cells: presence of glucocorticoid receptor alpha in mitochondria and of glucocorticoid receptor beta in nucleoli
  International Journal of Biochemistry and Cell Biology, 2005, 37(12), 2544-2558.
 Web of Science® Times Cited: 35

Zbigniew Madeja, Jolanta Sroka, Christina Nyström, Linda Björkhem-Bergman, Tomas Nordman, Anastasios Damdimopoulos, Ivan Nalvarte, Lennart C. Eriksson, Giannis Spyrou, Jerker M. Olsson and Mikael Björnstedt
  The role of thioredoxin reductase activity in selenium-induced cytotoxicity
  Biochemical Pharmacology, 2005, 69(12), 1765-1772.
 Web of Science® Times Cited: 23

Anastasios E. Damdimopoulos, Antonio Miranda-Vizuete, Eckardt Treuter, Jan-Åke Gustafsson and Giannis Spyrou
  An alternative splicing variant of the selenoprotein thioredoxin reductase is a modulator of estrogen signaling
  Journal of Biological Chemistry, 2004, 279(37), 38721-38729.

Ivan Nalvarte, Anastasios E Damdimopoulos and Giannis Spyrou
  Human mitochondrial thioredoxin reductase reduces cytochrome c and confers resistance to complex III inhibition
  Free Radical Biology & Medicine, 2004, 36(10), 1270-1278.

Ivan Nalvarte, Anastasios E Damdimopoulos, Christina Nystöm, Tomas Nordman, Antonio Miranda-Vizuete, Jerker M. Olsson, Lennart Eriksson, Mikael Björnstedt, Elias S.J. Arnér and Giannis Spyrou
  Overexpression of enzymatically active human cytosolic and mitochondrial thioredoxin reductase in HEK-293 cells: Effect on cell growth and differentiation
  Journal of Biological Chemistry, 2004, 279(52), 54510-54517.

Serguei A. Stroev, Tatjana S. Gluschenko, Ekaterina I. Tjulkova, Giannis Spyrou, Elena A. Rybnikova, Michail O. Samoilov and Markku Pelto-Huikko
  Preconditioning enhances the expression of mitochondrial antioxidant thioredoxin-2 in the forebrain of rats exposed to severe hypobaric hypoxia
  Journal of Neuroscience Research, 2004, 78(4), 563-569.

Christine M. Sadek, Alberto Jiménez, Anastasios E Damdimopoulos, Thomas Kieselbach, Magnus Nord, Jan-Åke Gustafsson, Giannis Spyrou, Elaine C. Davis, Richard Oko, Frans A. van der Hoorn and Antonio Miranda-Vizuete
  Characterization of human thioredoxin-like 2. A novel microtubule-binding thioredoxin expressed predominantly in the cilia of lung airway epithelium and spermatid manchette and axoneme
  Journal of Biological Chemistry, 2003, 278(15), 13133-13142.

Paula M Cunnea, Antonio Miranda-Vizuete, Gloria Bertoli, Thomas Simmen, Anastasios E Damdimopoulos, Stefan Hermann, Saku Leinonen, Markku Pelto Huikko, Jan-Ake Gustafsson, Roberto Sitia and Giannis Spyrou
  ERdj5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stress.
  Journal of Biological Chemistry, 2003, 278(2), 1059-66.

Tomas Nordman, Ling Xia, Linda Björkhem-Bergman, Anastassios Damdimopoulos, Ivan Nalvarte, Elias S.J. Arnér, Giannis Spyrou, Lennart C. Eriksson, Mikael Björnstedt and Jerker M. Olsson
  Regeneration of the antioxidant ubiquinol by lipoamide dehydrogenase, thioredoxin reductase and glutathione reductase
  Biofactors, 2003, 18(1-4), 45-50.
 Web of Science® Times Cited: 27

Ling Xia, Tomas Nordman, Jerker M. Olsson, Anastassios Damdimopoulos, Linda Björkhem-Bergman, Ivan Nalvarte, Lennart C. Eriksson, Elias S. J. Arnér, Giannis Spyrou and Mikael Björnstedt
  The mammalian cytosolic selenoenzyme thioredoxin reductase reduces ubiquinone. A novel mechanism for defense against oxidative stress
  Journal of Biological Chemistry, 2003, 278(4), 2141-2146.

Alberto Jiménez, Richard Oko, Jan-Åke Gustafsson, Giannis Spyrou, Markku Pelto-Huikko and Antonio Miranda-Vizuete
  Cloning, expression and characterization of mouse spermatid specific thioredoxin-1 gene and protein
  Molecular human reproduction, 2002, 8(8), 710-718.

Antonio Miranda-Vizuete and Giannis Spyrou
  Genomic organization and identification of a novel alternative splicing variant of mouse mitochondrial thioredoxin reductase (TrxR2) gene
  Molecules and Cells, 2002, 13(3), 488-492.

Anastasios E. Damdimopoulos, Antonio Miranda-Vizuete, Markku Pelto-Huikko, Jan-Åke Gustafsson and Giannis Spyrou
  Human mitochondrial thioredoxin. Involvement in mitochondrial membrane potential and cell death
  Journal of Biological Chemistry, 2002, 277(36), 33249-33257.

M. O. Samoilov, E. A. Rybnikova, E. I. Tjulkova, Giannis Spyrou and M. Pelto-Huikko
  The mitochondrial antioxidants thioredoxin-2 and Mn-superoxide dismutase are involved in the mechanisms of brain hypoxic tolerance
  Doklady. Biological sciences, 2002, 387(1-6), 498-500.

Toru Tanaka, Fumihito Hosoi, Yuko Yamaguchi-Iwai, Hajime Nakamura, Hiroshi Masutani, Shugo Ueda, Akira Nishiyama, Shunichi Takeda, Hiromi Wada, Giannis Spyrou and Junji Yodoi
  Thioredoxin-2 (TRX-2) is an essential gene regulating mitochondria-dependent apoptosis
  EMBO Journal, 2002, 21(7), 1695-703.

Giannis Spyrou, William Wilson, Alicia C. Padilla, Arne Holmgren and Antonio Miranda-Vizuete
  A genome-wide survey of human thioredoxin and glutaredoxin family pseudogenes
  Human Genetics, 2001, 109(4), 429-439.

Elias S. J. Arnér, H. Nakamura, Tetsuro Sasada, Junji Yodoi, Arne Holmgren and Giannis Spyrou
  Analysis of the inhibition of mammalian thioredoxin, thioredoxin reductase, and glutaredoxin by cis-diamminedichloroplatinum (II) and its major metabolite, the glutathione-platinum complex
  Free Radical Biology & Medicine, 2001, 31(10), 1170-1178.

Antonio Miranda-Vizuete, Johanna Ljung, Anastasios E. Damdimopoulos, Jan-Åke Gustafsson, Richard Oko, Markku Pelto-Huikko and Giannis Spyrou
  Characterization of Sptrx, a novel member of the thioredoxin family specifically expressed in human spermatozoa
  Journal of Biological Chemistry, 2001, 276(34), 31567-31574.

A. Miranda-Vizuete and Giannis Spyrou
  Identification of the first human glutaredoxin pseudogene localized to human chromosome 20q11.2.
  DNA Sequence, 2001, 11(6), 535-539.

C. M. Sadek, A. E. Damdimopoulos, M. Pelto-Huikko, J. A. Gustafsson, G Spyrou and A Miranda-Vizuete
  Sptrx-2, a fusion protein composed of one thioredoxin and three tandemly repeated NDP-kinase domains is expressed in human testis germ cells
  Genes to Cells, 2001, 6(12), 1077-1090.

Elena Rybnikova, A. E. Damdimopoulos, Jan-Åke Gustafsson, Giannis Spyrou and M. Pelto-Huikko
  Expression of novel antioxidant thioredoxin-2 in the rat brain
  European Journal of Neuroscience, 2000, 12(5), 1669-1678.

Antonio Miranda-Vizuete and Giannis Spyrou
  Genomic structure and chromosomal localization of human thioredoxin-like protein gene (txl)
  Mitochondrial DNA, 2000, 10(6), 419-424.

Antonio Miranda-Vizuete and Giannis Spyrou
  Identification of a novel thioredoxin-1 pseudogene on human chromosome 10
  Mitochondrial DNA, 2000, 10(6), 411-414.

José Rafael Pedrajas, Antonio Miranda-Vizuete, Negin Javanmardy, Jan-Åke Gustafsson and Giannis Spyrou
  Mitochondria of Saccharomyces cerevisiae contain one-conserved cysteine type peroxiredoxin with thioredoxin peroxidase activity
  Journal of Biological Chemistry, 2000, 275(21), 16296-16301.

Antonio Miranda-Vizuete, Anastasios E. Damdimopoulos and Giannis Spyrou
  The mitochondrial thioredoxin system
  Antioxidants and Redox Signaling, 2000, 2(4), 801-810.

Antonio Miranda-Vizuete, Anastasios E. Damdimopoulos and Giannis Spyrou
  cDNA cloning, expression and chromosomal localization of the mouse mitochondrial thioredoxin reductase gene(1)
  Biochimica et Biophysica Acta, 1999, 1447(1), 113-118.

A. Miranda-Vizuete, J. R. Pedrajas, A. E. Damdimopoulos and Giannis Spyrou
  Cloning and sequencing of mouse glutaredoxin (grx) cDNA
  Mitochondrial DNA, 1999, 10(3), 179-182.

E. Treuter, Lotta Johansson, J. S. Thomsen, A. Wärnmark, J. Leers, M. Pelto-Huikko, Maria Sjöberg, A. P. Wright, Giannis Spyrou and Jan-Åke Gustafsson
  Competition between thyroid hormone receptor-associated protein (TRAP) 220 and transcriptional intermediary factor (TIF) 2 for binding to nuclear receptors. Implications for the recruitment of TRAP and p160 coactivator complexes
  Journal of Biological Chemistry, 1999, 274(10), 6667-6677.

A. Miranda-Vizuete, A. E. Damdimopoulos, J. R. Pedrajas, Jan-Åke Gustafsson and Giannis Spyrou
  Human mitochondrial thioredoxin reductase cDNA cloning, expression and genomic organization
  European Journal of Biochemistry, 1999, 261(2), 405-412.

José R. Pedrajas, Effie Kosmidou, Antonio Miranda-Vizuete, Jan-Åke Gustafsson, Anthony P. H. Wright and Giannis Spyrou
  Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae
  Journal of Biological Chemistry, 1999, 274(10), 6366-6373.

T. Sasada, H. Nakamura, S. Ueda, N. Sato, Y. Kitaoka, Y. Gon, A. Takabayashi, Giannis Spyrou, Arne Holmgren and J. Yodoi
  Possible involvement of thioredoxin reductase as well as thioredoxin in cellular sensitivity to cis-diamminedichloroplatinum (II)
  Free Radical Biology & Medicine, 1999, 27(5-6), 504-514.

L. Johansson, J. S. Thomsen, A. E. Damdimopoulos, Giannis Spyrou, Jan-Åke Gustafsson and E. Treuter
  The orphan nuclear receptor SHP inhibits agonist-dependent transcriptional activity of estrogen receptors ERalpha and ERbeta
  Journal of Biological Chemistry, 1999, 274(1), 345-353.

Kai Jiang, Giannis Spyrou and Åke Rökaeus
  Characterization of phorbolester-inducible human neuronal factors involved in trans-activation of the galanin gene
  Biochemical and Biophysical Research Communications - BBRC, 1998, 246(1), 192-198.

D. Nikitovic, A. Holmgren and Giannis Spyrou
  Inhibition of AP-1 DNA binding by nitric oxide involving conserved cysteine residues in Jun and Fos
  Biochemical and Biophysical Research Communications - BBRC, 1998, 242(1), 109-112.

A Miranda-Vizuete, Jan-.Åke Gustafsson and Giannis Spyrou
  Molecular cloning and expression of a cDNA encoding a human thioredoxin-like protein
  Biochemical and Biophysical Research Communications - BBRC, 1998, 243(1), 284-288.

Åke Rökaeus, Kai Jiang, Giannis Spyrou and James A. Waschek
  Transcriptional control of the galanin gene. Tissue-specific expression and induction by NGF, protein kinase C, and estrogen
  Annals of the New York Academy of Sciences, 1998, 863, 1-13.

Giannis Spyrou, E. Enmark, A. Miranda-Vizuete and Jan-Åke Gustafsson
  Cloning and expression of a novel mammalian thioredoxin
  Journal of Biological Chemistry, 1997, 272(5), 2936-2941.

A. Miranda-Vizuete, A. E. Damdimopoulos, Jan-Åke Gustafsson and Giannis Spyrou
  Cloning, expression, and characterization of a novel Escherichia coli thioredoxin
  Journal of Biological Chemistry, 1997, 272(49), 30841-30847.

A. Vlamis-Gardikas, F. Åslund, Giannis Spyrou, T. Bergman and A. Holmgren
  Cloning, overexpression, and characterization of glutaredoxin 2, an atypical glutaredoxin from Escherichia coli
  Journal of Biological Chemistry, 1997, 272(17), 11236-11243.

M. Björnstedt, S. Kumar, L. Björkhem, Giannis Spyrou and A. Holmgren
  Selenium and the thioredoxin and glutaredoxin systems
  Biomedical and environmental sciences, 1997, 10(2-3), 271-279.

A. Miranda-Vizuete and Giannis Spyrou
  The novel oxidoreductase KDRF (KM-102-derived reductase-like factor) is identical with human thioredoxin reductase
  Biochemical Journal, 1997, 325 ( Pt 1), 287-288.

Bita Sahaf, Anita Söderberg, Giannis Spyrou, Anna-Maria Barral, Klas Pekkari, Arne Holmgren and Anders Rosén
  Thioredoxin Expression and Localization in Human Cell Lines: Detection of Full-Length and Truncated Species
  Experimental Cell Research, 1997, 236(1), 181-192.

D. Lallemand, Giannis Spyrou, M. Yaniv and C. M. Pfarr
  Variations in Jun and Fos protein expression and AP-1 activity in cycling, resting and stimulated fibroblasts
  Oncogene, 1997, 14(7), 819-830.

S. Hirai, M. Izawa, S. Osada, Giannis Spyrou and S. Ohno
  Activation of the JNK pathway by distantly related protein kinases, MEKK and MUK
  Oncogene, 1996, 12(3), 641-650.

Giannis Spyrou and A. Holmgren
  Deoxyribonucleoside triphosphate pools and growth of glutathione-depleted 3T6 mouse fibroblasts
  Biochemical and Biophysical Research Communications - BBRC, 1996, 220(1), 42-46.

C. A. Padilla, Giannis Spyrou and A. Holmgren
  High-level expression of fully active human glutaredoxin (thioltransferase) in E. coli and characterization of Cys7 to Ser mutant protein
  FEBS Letters, 1996, 378(1), 69-73.

M. Andersson, A. Holmgren and Giannis Spyrou
  NK-lysin, a disulfide-containing effector peptide of T-lymphocytes, is reduced and inactivated by human thioredoxin reductase. Implication for a protective mechanism against NK-lysin cytotoxicity
  Journal of Biological Chemistry, 1996, 271(17), 10116-10120.

Giannis Spyrou, M. Björnstedt, S. Skog and A. Holmgren
  Selenite and selenate inhibit human lymphocyte growth via different mechanisms
  Cancer Research, 1996, 56(19), 4407-4412.

Giannis Spyrou, M. Björnstedt, S. Kumar and A. Holmgren
  AP-1 DNA-binding activity is inhibited by selenite and selenodiglutathione
  FEBS Letters, 1995, 368(1), 59-63.

C. A. Padilla, E. Martínez-Galisteo, J. A. Bárcena, Giannis Spyrou and A. Holmgren
  Purification from placenta, amino acid sequence, structure comparisons and cDNA cloning of human glutaredoxin
  European Journal of Biochemistry, 1995, 227(1-2), 27-34.

J. Chen, V. Stewart, Giannis Spyrou, F. Hilberg, E. F. Wagner and F. W. Alt
  Generation of normal T and B lymphocytes by c-jun deficient embryonic stem cells
  Immunity, 1994, 1(1), 65-72.

C. M. Pfarr, F. Mechta, Giannis Spyrou, D. Lallemand, S. Carillo and M. Yaniv
  Mouse JunD negatively regulates fibroblast growth and antagonizes transformation by ras
  Cell, 1994, 76(4), 747-760.

S. Bohm, M. Bakke, M. Nilsson, U. M. Zanger, Giannis Spyrou and J. Lund
  Cooperating nonconsensus cAMP-responsive elements are mediators of adrenocorticotropin-induced VL30 transcription in steroidogenic adrenal cells
  Journal of Biological Chemistry, 1993, 268(6), 3952-3963.

F. Thierry, Giannis Spyrou, M. Yaniv and P. Howley
  Two AP1 sites binding JunB are essential for human papillomavirus type 18 transcription in keratinocytes
  Journal of Virology, 1992, 66(6), 3740-3748.

Giannis Spyrou, E Haggård-Ljungquist, M. Krook, H. Jörnvall, E. Nilsson and Peter Reichard
  Characterization of the flavin reductase gene (fre) of Escherichia coli and construction of a plasmid for overproduction of the enzyme
  Journal of Bacteriology, 1991, 173(12), 3673-3679.

M. Castellazzi, Giannis Spyrou, N. La Vista, J-P Dangy, F. Piu, M. Yaniv and G. Brun
  Overexpression of c-jun, junB, or junD affects cell growth differently
  Proceedings of the National Academy of Sciences of the United States of America, 1991, 88(20), 8890-8894.

V. Doucas, Giannis Spyrou and M. Yaniv
  Unregulated expression of c-Jun or c-Fos proteins but not Jun D inhibits oestrogen receptor activity in human breast cancer derived cells
  EMBO Journal, 1991, 10(8), 2237-2245.

Giannis Spyrou and Peter Reichard
  Intracellular compartmentation of deoxycytidine nucleotide pools in S phase mouse 3T3 fibroblasts
  Journal of Biological Chemistry, 1989, 264(2), 960-964.

T. Spasokukotskaja, Giannis Spyrou and M. Staub
  Deoxycytidine is salvaged not only into DNA but also into phospholipid precursors
  Biochemical and Biophysical Research Communications - BBRC, 1988, 155(2), 923-929.

Giannis Spyrou and Peter Reichard
  Dynamics of the thymidine triphosphate pool during the cell cycle of synchronized 3T3 mouse fibroblasts
  Mutation research, 1988, 200(1-2), 37-43.
 Web of Science® Times Cited: 28

Giannis Spyrou and Peter Reichard
  Compartmentation of dCTP pools. Evidence from deoxyliponucleotide synthesis
  Journal of Biological Chemistry, 1987, 262(34), 16425-16432.
 Web of Science® Times Cited: 40

Giannis Spyrou and Peter Reichard
  Ribonucleotides are not channeled into DNA in permeabilized mammalian cells
  Biochemical and Biophysical Research Communications - BBRC, 1983, 115(3), 1022-1026.

* Social media data based on publications from 2011 to present and with a DOI; data delivered by Altmetric.com.


Responsible for this page: Peter Berkesand
Last updated: 2010-08-30