Publications for Alexandru Dasu
Co-author map based on ISI articles 2007-

Keywords

tumours tumour treatment tissues tissue risk radiotherapy radiation prostate patients oxygenation oxygen model hypoxic hypoxia electrode doses dose clinical cells

Journal Articles

Iuliana Toma-Dasu and Alexandru Dasu
  Towards multidimensional radiotherapy - key challenges for treatment individualisation
  Computational & Mathematical Methods in Medicine, 2014, 2014, Article ID 934380.

Iuliana Toma-Dasu, Helena Sandström, Pierre Barsoum and Alexandru Dasu
  To fractionate or not to fractionate? That is the question for the radiosurgery of hypoxic tumors
  Journal of Neurosurgery, 2014, 121, 110-115.

Anna M. Flejmer, Dan Josefsson, Mats Nilsson, Margaretha Stenmarker and Alexandru Dasu
  Clinical implications of the ISC technique for breast cancer radiotherapy and comparison with clinical recommendations
  Anticancer Research, 2014, 34(7), 3563-3568.
   Fulltext  PDF  

Emely Lindblom, Alexandru Dasu, Ingmar Lax and Iuliana Toma-Dasu
  Survival and tumour control probability in tumours with heterogeneous oxygenations: A comparison between the linear-quadratic and the universal survival curve models for high doses
  Acta Oncologica, 2014, 53(8), 1035-1040.

Oscar Ardenfors, Dan Josefsson and Alexandru Dasu
  Are IMRT treatments in the head and neck region increasing the risk of secondary cancers?
  Acta Oncologica, 2014, 53(8), 1041-1047.

Irena Gudowska, Oscar Ardenfors, Iuliana Toma-Dasu and Alexandru Dasu
  Radiation burden from secondary doses to patients undergoing radiation therapy with photons and light ions and radiation doses from imaging modalities
  Radiation Protection Dosimetry, 2014, 161(1-4), 357-362.

Iuliana Toma-Dasu and Alexandru Dasu
  Quantitative hypoxia imaging for treatment planning of radiotherapy
  Advances in Experimental Medicine and Biology, 2014, 812, 143-148.

Emely Lindblom, Laura Antonovic, Alexandru Dasu, Ingmar Lax, Peter Wersäll and Iuliana Toma-Dasu
  Treatment fractionation for stereotactic radiotherapy of lung tumours: a modelling study of the influence of chronic and acute hypoxia on tumour control probability
  Radiation Oncology, 2014, 9, Article ID 149.
   Fulltext  PDF  

Laura Antonovic, Emely Lindblom, Alexandru Dasu, Niels Bassler, Yoshiya Furusawa and Iuliana Toma-Dasu
  Clinical oxygen enhancement ratio of tumors in carbon ion radiotherapy: the influence of local oxygenation changes
  Journal of radiation research, 2014, 55(5), 902-911.
   Fulltext  PDF  

Helena Sandström, Alexandru Dasu and Iuliana Toma-Dasu
  Radiobiological framework for the evaluation of stereotactic radiosurgery plans for invasive brain tumours
  ISRN Oncology, 2013, 2013, Article ID 527251.
   Fulltext  PDF  

Jack F. Fowler, Iuliana Toma-Dasu and Alexandru Dasu
  Is the α/β ratio for prostate tumours really low and does it vary with the level of risk at diagnosis?
  Anticancer Research, 2013, 33(3), 1009-1011.
 Web of Science® Times Cited: 3

Iuliana Toma-Dasu and Alexandru Dasu
  Modelling tumour oxygenation, reoxygenation and implications on treatment outcome
  Computational and Mathematical Methods in Medicine, 2013, 2013, Article ID 141087.
   Fulltext  PDF  
 Web of Science® Times Cited: 3

Alexandru Dasu and Iuliana Toma-Dasu
  Impact of variable RBE on proton fractionation
  Medical physics (Lancaster), 2013, 40(1), Article ID 011705.
 Web of Science® Times Cited: 3

luliana Toma-Dasu and Alexandru Dasu
  Biologically-optimised IMRT based on molecular imaging of tumour hypoxia - the impact of the tracer used
  IFMBE Proceedings, 2013, 39, 1742-1745.

Alexandru Dasu and Iuliana Toma-Dasu
  Dose painting by numbers - do the practical limitations of the technique decrease or increase the probability of controlling tumours?
  IFMBE Proceedings, 2013, 39, 1731-1734.

Iuliana Toma-Dasu, Johan Uhrdin, Laura Antonovic, Alexandru Dasu, Sandra Nuyts, Piet Dirix, Karin Haustermans and Anders Brahme
  Dose prescription and treatment planning based on FMISO-PET hypoxia
  Acta Oncologica, 2012, 51(2), 222-230.
 Web of Science® Times Cited: 12

Aijun Sun, Silvia Johansson, Ingela Turesson, Alexandru Daşu and Jens Sörensen
  Imaging tumor perfusion and oxidative metabolism in patients with head-and-neck cancer using 1-[(11)C]-acetate PET during radiotherapy: preliminary results
  International journal of radiation oncology, biology, physics, 2012, 82(2), 554-560.

Alexandru Dasu and Iuliana Toma-Dasu
  Prostate alpha/beta revisited – an analysis of clinical results from 14168 patients
  Acta Oncologica, 2012, 51(8), 963-974.
 Web of Science® Times Cited: 14

Alexandru Daşu, Iuliana Toma-Daşu, Lars Franzén, Anders Widmark and Per Nilsson
  Secondary malignancies from prostate cancer radiation treatment: a risk analysis of the influence of target margins and fractionation patterns
  International journal of radiation oncology, biology, physics, 2011, 79(3), 738-746.

Alexandru Daşu, Iuliana Toma-Daşu, Lars Franzén, Anders Widmark and Per Nilsson
  The risk for secondary cancers in patients treated for prostate carcinoma – an analysis with the competition dose response model
  IFMBE Proceedings, 2009, 25/III, 237-240.

Iuliana Toma-Daşu, Johan Uhrdin, Alexandru Daşu and Anders Brahme
  Therapy optimization based on non-linear uptake of PET tracers versus "linear dose painting"
  IFMBE Proceedings, 2009, 25/I, 221-224.

Iuliana Toma-Daşu, Alexandru Daşu and Anders Brahme
  Dose prescription and optimisation based on tumour hypoxia
  Acta Oncologica, 2009, 48(8), 1181-1192.

Iuliana Toma-Daşu, Alexandru Daşu and Anders Brahme
  Quantifying tumour hypoxia by PET imaging--a theoretical analysis
  Advances in Experimental Medicine and Biology, 2009, 645, 267-272.

Alexandru Daşu and Iuliana Toma-Daşu
  The relationship between vascular oxygen distribution and tissue oxygenation
  Advances in Experimental Medicine and Biology, 2009, 645, 255-260.

Alexandru Daşu and Iuliana Toma-Daşu
  In response to Dr. Karger et al.
  International Journal of Radiation Oncology, Biology, Physics, 2008, 70(5), 1614-1615.

Alexandru Daşu and Iuliana Toma-Daşu
  Treatment modelling: the influence of micro-environmental conditions
  Acta Oncologica, 2008, 47(5), 896-905.

Alexandru Daşu and Iuliana Toma-Daşu
  What is the clinically relevant relative biologic effectiveness? A warning for fractionated treatments with high linear energy transfer radiation
  International Journal of Radiation Oncology, Biology, Physics, 2008, 70(3), 867-874.

Alexandru Daşu and Iuliana Toma-Daşu
  Vascular oxygen content and the tissue oxygenation--a theoretical analysis
  Medical physics (Lancaster), 2008, 35(2), 539-545.

Alexandru Dasu
  Treatment planning optimisation based on imaging tumour proliferation and cell density
  Acta Oncologica, 2008, 47(7), 1221-1228.

Alexandru Dasu
  Is the alpha/beta value for prostate tumours low enough to be safely used in clinical trials?
  Clinical Oncology, 2007, 19(5), 289-301.

Iuliana Toma-Daşu, Alexandru Daşu and Mikael Karlsson
  Theoretical simulation of tumour hypoxia measurements
  Advances in Experimental Medicine and Biology, 2006, 578(12), 369-374.

Alexandru Daşu and Iuliana Toma-Daşu
  Theoretical simulation of tumour oxygenation--practical applications
  Advances in Experimental Medicine and Biology, 2006, 578(12), 357-362.

Alexandru Daşu and Jack F Fowler
  Comments on "Comparison of in vitro and in vivo alpha/beta ratios for prostate cancer"
  Physics in Medicine and Biology, 2005, 50(6), L1-4.

Iuliana Toma-Daşu, Alexandru Daşu and Mikael Karlsson
  Conversion of polarographic electrode measurements--a computer based approach
  Physics in Medicine and Biology, 2005, 50(19), 4581-4591.

Alexandru Daşu and Iuliana Toma-Daşu
  Dose-effect models for risk - relationship to cell survival parameters
  Acta Oncologica, 2005, 44(8), 829-835.

Alexandru Daşu, Iuliana Toma-Daşu and Mikael Karlsson
  The effects of hypoxia on the theoretical modelling of tumour control probability
  Acta Oncologica, 2005, 44(6), 563-571.

Alexandru Daşu, Iuliana Toma-Daşu, Jörgen Olofsson and Mikael Karlsson
  The use of risk estimation models for the induction of secondary cancers following radiotherapy
  Acta Oncologica, 2005, 44(4), 339-347.

Iuliana Toma-Daşu, Alexandru Daşu and Mikael Karlsson
  The relationship between temporal variation of hypoxia, polarographic measurements and predictions of tumour response to radiation
  Physics in Medicine and Biology, 2004, 49(19), 4463-4475.

Iuliana Toma-Daşu, Alexandru Daşu, Anthony Waites and Juliana Denekamp
  Computer simulation of oxygen microelectrode measurements in tissues
  Advances in Experimental Medicine and Biology, 2003, 510, 157-161.

Alexandru Daşu and Juliana Denekamp
  The impact of tissue microenvironment on treatment simulation
  Advances in Experimental Medicine and Biology, 2003, 510, 63-67.

Alexandru Daşu, Iuliana Toma-Daşu and Jack F. Fowler
  Should single or distributed parameters be used to explain the steepness of tumour control probability curves?
  Physics in Medicine and Biology, 2003, 48(3), 387-397.

Alexandru Daşu, Iuliana Toma-Daşu and Mikael Karlsson
  Theoretical simulation of tumour oxygenation and results from acute and chronic hypoxia
  Physics in Medicine and Biology, 2003, 48(17), 2829-2842.

Iuliana Toma-Daşu, Alexandru Daşu, Anthony Waites, Juliana Denekamp and Jack F Fowler
  Theoretical simulation of oxygen tension measurement in the tissue using a microelectrode: II. Simulated measurements in tissues
  Radiotherapy and Oncology, 2002, 64(1), 109-118.

Iuliana Toma-Daşu, Anthony Waites, Alexandru Daşu and Juliana Denekamp
  Theoretical simulation of oxygen tension measurement in tissues using a microelectrode: I. The response function of the electrode 
  Physiological Measurement, 2001, 22(4), 713-725.

Iuliana Livia Daşu, Alexandru Daşu, Juliana Denekamp and Jack F Fowler
  Comments on 'Standard effective doses for proliferative tumours'
  Physics in Medicine and Biology, 2000, 45(10), L45-L50.

Alexandru Daşu and Juliana Denekamp
  Inducible repair and intrinsic radiosensitivity: a complex but predictable relationship?
  Radiation Research, 2000, 153(3), 279-288.

Alexandru Daşu and Juliana Denekamp
  Superfractionation as a potential hypoxic cell radiosensitizer: prediction of an optimum dose per fraction
  International Journal of Radiation Oncology, Biology, Physics, 1999, 43(5), 1083-1094.

Juliana Denekamp and Alexandru Daşu
  Inducible repair and the two forms of tumour hypoxia--time for a paradigm shift
  Acta Oncologica, 1999, 38(7), 903-918.

Juliana Denekamp, Alexandru Daşu, Anthony Waites and Bo Littbrand
  Hyperfractionation as an effective way of overcoming radioresistance
  International Journal of Radiation Oncology, Biology, Physics, 1998, 42(4), 705-709.

Alexandru Daşu and Juliana Denekamp
  New insights into factors influencing the clinically relevant oxygen enhancement ratio
  Radiotherapy and Oncology, 1998, 46(3), 269-277.

Juliana Denekamp, Alexandru Daşu and Anthony Waites
  Vasculature and microenvironmental gradients: the missing links in novel approaches to cancer therapy?
  Advances in Enzyme Regulation, 1998, 38(1), 281-299.

Alexandru Daşu, Per-Olov Löfroth and Göran Wickman
  Liquid ionization chamber measurements of dose distributions in small 6 MV photon beams
  Physics in Medicine and Biology, 1998, 43(1), 21-36.

Chapters in Books

Alexandru Dasu and Iuliana Toma-Dasu
  Long-term effects and secondary tumors
  Comprehensive Biomedical Physics, Volume 9: Radiation Therapy Physics and Treatment Optimization, Elsevier, 2014, 223-233.


Alexandru Dasu
  Radiobiology of prostate cancer
  Robotic Radiosurgery. Treating Prostate Cancer and Related Genitourinary Applications, Springer Berlin/Heidelberg, 2012, 79-101.


Iuliana Toma-Daşu, Alexandru Daşu and Anders Brahme
  Influence of acute tumour hypoxia on radiation therapy outcome
  AAPM Symposium Proceedings No. 14: Physical, Chemical and Biological Targeting in Radiation Oncology, Medical Physics Publishing, 2005, 111-117.